3,3-diphenyl-8-hydroxy-9-carbopropoxy-3H-naphtho[2,1-b]pyran | 163672-88-6

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 黄酮类化合物
• 英文名称: 3,3-diphenyl-8-hydroxy-9-carbopropoxy-3H-naphtho[2,1-b]pyran
• 英文别名: Propyl 8-hydroxy-3,3-diphenylbenzo[f]chromene-9-carboxylate
• CAS: 163672-88-6
• 化学式: C₂₉H₂₄O₄
• 分子量: 436.507
• InChiKey: ITVNPMZGONPKQV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.6
• 重原子数：
  33
• 可旋转键数：
  6
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.14
• 拓扑面积：
  55.8
• 氢给体数：
  1
• 氢受体数：
  4

文献信息

• EP0710367A4
  申请人：——

  公开号：EP0710367A4

  公开（公告）日：1996-05-15
• PHOTOCHROMIC SUBSTITUTED NAPHTHOPYRAN COMPOUNDS
  申请人：PPG Industries Ohio, Inc.

  公开号：EP0710367B1

  公开（公告）日：2000-08-30
• JPH09505271A
  申请人：——

  公开号：JPH09505271A

  公开（公告）日：1997-05-27
• Photochromic articles that activate behind ultraviolet radiation blocking transparencies and methods for preparation
  申请人：——

  公开号：US20040185268A1

  公开（公告）日：2004-09-23

  Described are photochromic articles that include a substrate and at least one photochromic material adapted to change from an unactivated state to an activated state by exposure to radiation substantially in a wavelength range from 380 to 410 nanometers (nm) when measured over a wavelength range of from 380 to 700 nm. The photochromic articles demonstrate a photochromic response when activated behind an ultraviolet blocking transparency such as an automotive windshield. For example, the photochromic articles retain at least 12 percent of the activation measured as change in optical density or delta OD under outdoor simulating conditions in the Outdoor Test when tested under conditions simulating an eyeglass wearer behind an automotive windshield in the Behind the Windshield Test. Methods for producing the aforedescribed photochromic articles are also described.
• PHOTOCHROMIC POLYDIORGANOSILOXANE VINYLIC CROSSLINKERS
  申请人：Alcon Inc.

  公开号：US20210284806A1

  公开（公告）日：2021-09-16

  The invention provides a class of photochromic polydiorganosiloxane vinylic crosslinkers. Each of the photochromic polydiorganosiloxane vinylic crosslinkers of the invention comprise (1) a polydiorganosiloxane polymer chain comprising dimethylsiloxane units and photochromic siloxane unit having one methyl substituent and one organic substituent having a photochromic moiety that capable of undergoing a reversible color change upon exposure to UV-irradiation or high-energy-violet light; (2) two terminal ethylenically-unsaturated groups. The invention also provides a soft photochromic contact lens, especially a photochromic silicone hydrogel contact lens, which comprises a crosslinked polymeric material comprising repeating units of at least one of such a class of photochromic polydiorganosiloxane vinylic crosslinkers. The invention further provides a method of producing a photochromic contact lens from a polymerizable composition comprising at least one of such a class of photochromic polydiorganosiloxane vinylic crosslinkers.