N-cyclohexyl-2-(2-fluorophenyl)-5-methylimidazo[1,2-a]pyridin-3-amine | 1049021-32-0

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: N-cyclohexyl-2-(2-fluorophenyl)-5-methylimidazo[1,2-a]pyridin-3-amine
• CAS: 1049021-32-0
• 化学式: C₂₀H₂₂FN₃
• 分子量: 323.413
• InChiKey: AXQAQGKDPRMJMR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.1
• 重原子数：
  24
• 可旋转键数：
  3
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.35
• 拓扑面积：
  29.3
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• [EN] NON-NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS<br/>[FR] INHIBITEURS NON NUCLÉOSIDIQUES DE LA TRANSCRIPTASE INVERSE
  申请人：SALK INSTITUITE FOR BIOLOG STU

  公开号：WO2009061856A1

  公开（公告）日：2009-05-14

  Disclosed herein are antiviral agents, in particular non-nucleoside reverse transcriptase inhibitors (NNRTIs) of the formula. Also disclosed are methods of making the NNRTIs, as well as compositions that include such NNRTIs and methods of their use for treating viral infections, in particular retroviral infections, such as HIV infection.

  本文披露了抗病毒药物，特别是式中的非核苷类逆转录酶抑制剂（NNRTIs）。还披露了制备NNRTIs的方法，以及包含这些NNRTIs的组合物和它们用于治疗病毒感染的方法，特别是逆转录病毒感染，如HIV感染。
• NON-NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS
  申请人：Elleder Daniel

  公开号：US20100292232A1

  公开（公告）日：2010-11-18

  Disclosed herein are antiviral agents, in particular non-nucleoside reverse transcriptase inhibitors (NNRTIs) of the formula Also disclosed are methods of making the NNRTIs, as well as compositions that include such NNRTIs and methods of their use for treating viral infections, in particular retroviral infections, such as HIV infection.