N-[4-(benzo[d]thiazol-2-yl)-3-(vinyloxy)phenyl]acetamide | 1312163-31-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N-[4-(benzo[d]thiazol-2-yl)-3-(vinyloxy)phenyl]acetamide
• 英文别名: N-[4-(1,3-benzothiazol-2-yl)-3-ethenoxyphenyl]acetamide
• CAS: 1312163-31-7
• 化学式: C₁₇H₁₄N₂O₂S
• 分子量: 310.376
• InChiKey: FJYSFQLNGRLMHV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.7
• 重原子数：
  22
• 可旋转键数：
  4
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.06
• 拓扑面积：
  79.5
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  2-(4-acetylamino-2-hydroxyphenyl)benzothiazole 在 potassium tert-butylate 、 potassium carbonate 作用下， 以 二甲基亚砜 、 N,N-二甲基甲酰胺 为溶剂， 反应 4.0h， 生成 N-[4-(benzo[d]thiazol-2-yl)-3-(vinyloxy)phenyl]acetamide
  参考文献：
  名称：

  A “Reactive” Ratiometric Fluorescent Probe for Mercury Species

  摘要：

  A ratiometric fluorescent probe for mercury species is developed bused on the metal-promoted hydrolysis of a vinyl ether derivative of 2-(benzothiazol-2-yl)phenol in a buffer solution. The probe responds selectively to mercury species over various other metal ions with a marked fluorescence change from blue to cyan through the excited state intramolecular proton transfer (ESIPT) process. The fluorescence titration is complete with 0.5 equiv of HgCl2, which indicates that the probe also responds to organomercury species, RHgCl.

  DOI：

  10.1021/ol2011693

文献信息

• A “Reactive” Ratiometric Fluorescent Probe for Mercury Species
  作者：Mithun Santra、Basab Roy、Kyo Han Ahn

  DOI：10.1021/ol2011693

  日期：2011.7.1

  A ratiometric fluorescent probe for mercury species is developed bused on the metal-promoted hydrolysis of a vinyl ether derivative of 2-(benzothiazol-2-yl)phenol in a buffer solution. The probe responds selectively to mercury species over various other metal ions with a marked fluorescence change from blue to cyan through the excited state intramolecular proton transfer (ESIPT) process. The fluorescence titration is complete with 0.5 equiv of HgCl2, which indicates that the probe also responds to organomercury species, RHgCl.