1,4-bis(2,2'-bis(methoxymethoxy)-3,3'-diphenyl-[1,1'-binaphthalen]-6-yl)benzene | 1158868-67-7

• 分子结构分类: 有机化合物 - 木脂素、新木脂素和相关化合物 - 芳基萘木脂素
• 英文名称: 1,4-bis(2,2'-bis(methoxymethoxy)-3,3'-diphenyl-[1,1'-binaphthalen]-6-yl)benzene
• CAS: 1158868-67-7
• 化学式: C₇₈H₆₂O₈
• 分子量: 1127.35
• InChiKey: IQPVQKMWUSVZFJ-UHFFFAOYSA-N

物化性质

• 熔点：
  167-169 °C
• 密度：
  1.204±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  19.57
• 重原子数：
  86.0
• 可旋转键数：
  20.0
• 环数：
  13.0
• sp3杂化的碳原子比例：
  0.1
• 拓扑面积：
  73.84
• 氢给体数：
  0.0
• 氢受体数：
  8.0

反应信息

• 作为反应物：
  描述：

  1,4-bis(2,2'-bis(methoxymethoxy)-3,3'-diphenyl-[1,1'-binaphthalen]-6-yl)benzene 在 盐酸 、 水 作用下， 以 四氢呋喃 、 甲醇 为溶剂， 反应 20.0h， 以95%的产率得到6-[4-[6-Hydroxy-5-(2-hydroxy-3-phenylnaphthalen-1-yl)-7-phenylnaphthalen-2-yl]phenyl]-1-(2-hydroxy-3-phenylnaphthalen-1-yl)-3-phenylnaphthalen-2-ol
  参考文献：
  名称：

  Self-supported BINOL–Zn catalysts for heterogeneous enantioselective epoxidation of (E)-α,β-unsaturated ketones

  摘要：

  A class of chiral self-supported catalysts prepared from bis-BINOL ligands and diethyl zinc were successfully applied in the hetereogeneous enantioselective epoxidation of a range of (E)-alpha,beta-unsaturated ketones, affording the corresponding epoxy ketones in high enantioselectivity. The self-supported catalysts were easily recovered from the reaction mixture and were reusable for several consecutive runs. (C) 2009 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2009.02.151
• 作为产物：
  描述：

  (R)-6-iodo-3,3'-diiphenyl-2,2'-bis(methoxymethoxy)-1,1'-binaphthyl 、 1,4-苯二硼酸 在 potassium phosphate monohydrate 、 1,3-bis(2,4,6-trimethylphenyl)-imidazolium 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 以81%的产率得到1,4-bis(2,2'-bis(methoxymethoxy)-3,3'-diphenyl-[1,1'-binaphthalen]-6-yl)benzene
  参考文献：
  名称：

  Self-supported BINOL–Zn catalysts for heterogeneous enantioselective epoxidation of (E)-α,β-unsaturated ketones

  摘要：

  A class of chiral self-supported catalysts prepared from bis-BINOL ligands and diethyl zinc were successfully applied in the hetereogeneous enantioselective epoxidation of a range of (E)-alpha,beta-unsaturated ketones, affording the corresponding epoxy ketones in high enantioselectivity. The self-supported catalysts were easily recovered from the reaction mixture and were reusable for several consecutive runs. (C) 2009 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2009.02.151