N-(2-azidoethyl)-2-methylpropan-1-amine | 1376758-37-0

• 分子结构分类: 有机化合物 - 有机1,3-偶极化合物 - 烯丙基型1,3-偶极有机化合物
• 英文名称: N-(2-azidoethyl)-2-methylpropan-1-amine
• CAS: 1376758-37-0
• 化学式: C₆H₁₄N₄
• 分子量: 142.204
• InChiKey: AGOSMZCHCMAJOL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2
• 重原子数：
  10
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  26.4
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  N-(2-azidoethyl)-2-methylpropan-1-amine 在 盐酸 作用下， 以 四氢呋喃 为溶剂， 以1.46 g的产率得到
  参考文献：
  名称：

  Daisy Chain Assembly Formed from a Cucurbit[6]uril Derivative

  摘要：

  The building block synthesis of a derivative of CB[6] that bears a reactive propargyloxy group and its functionalization by click chemistry to yield 1 which contains a covalently attached isobutylammonium group is presented. Compound 1 undergoes self-assembly to yield a cyclic [c2] daisy chain assembly (1(2)) in water. The behavior of 1(2) in response to various stimuli (e.g., guests and CB[n] receptors) is described.

  DOI：

  10.1021/ol3011425
• 作为产物：
  描述：

  2-(2-甲基亚丙基氨基)乙醇 在 sodium tetrahydroborate 、 氯化亚砜 、 sodium azide 作用下， 以 甲醇 、 氯仿 、 水 为溶剂， 反应 1.0h， 生成 N-(2-azidoethyl)-2-methylpropan-1-amine
  参考文献：
  名称：

  Daisy Chain Assembly Formed from a Cucurbit[6]uril Derivative

  摘要：

  The building block synthesis of a derivative of CB[6] that bears a reactive propargyloxy group and its functionalization by click chemistry to yield 1 which contains a covalently attached isobutylammonium group is presented. Compound 1 undergoes self-assembly to yield a cyclic [c2] daisy chain assembly (1(2)) in water. The behavior of 1(2) in response to various stimuli (e.g., guests and CB[n] receptors) is described.

  DOI：

  10.1021/ol3011425