1,2,4,6,7-pentamethylindole | 99875-31-7

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吲哚及其衍生物
• 英文名称: 1,2,4,6,7-pentamethylindole
• CAS: 99875-31-7
• 化学式: C₁₃H₁₇N
• 分子量: 187.285
• InChiKey: YJIOFDUEIYCAJI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.5
• 重原子数：
  14
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.38
• 拓扑面积：
  4.9
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为反应物：
  描述：

  1,2,4,6,7-pentamethylindole 、 碘甲烷 以 甲醇 为溶剂， 反应 66.0h， 生成 1,2,3,3,4,6,7-heptamethylindoleninium iodide
  参考文献：
  名称：

  Crown ether-containing styryl dyes

  摘要：

  The method for the synthesis of indoles from nitropyridinium salts has been improved. A method for synthesizing novel derivatives of indoleninium quaternary salts has been developed. The condensation of indoleninium salts with formyl derivatives of crown ethers leading to styryl dyes is described. Photoisomerization and complexing of crown-ether dyes with ions of alkaline and alkaline-earth metals have been studied. The shift of the long-wave absorption maximum has been observed to depend on the size and charge density of the metal cation.

  DOI：

  10.1007/bf00699196
• 作为产物：
  描述：

  1,2,4,6-tetramethyl-3-nitropyridinium iodide 、 丁酮 在 甲胺 作用下， 反应 60.0h， 以31%的产率得到1,2,4,6,7-pentamethylindole
  参考文献：
  名称：

  Crown ether-containing styryl dyes

  摘要：

  The method for the synthesis of indoles from nitropyridinium salts has been improved. A method for synthesizing novel derivatives of indoleninium quaternary salts has been developed. The condensation of indoleninium salts with formyl derivatives of crown ethers leading to styryl dyes is described. Photoisomerization and complexing of crown-ether dyes with ions of alkaline and alkaline-earth metals have been studied. The shift of the long-wave absorption maximum has been observed to depend on the size and charge density of the metal cation.

  DOI：

  10.1007/bf00699196

文献信息

• Synthesis of indoles from pyridinium salts
  作者：S. P. Gromov、M. M. Bkhaumik、Yu. G. Bundel'

  DOI：10.1007/bf00546736

  日期：1987.4
• Indoles from 3-nitropyridinium salts 9. Methyl ethyl ketone N-methylimine in the indolization of 1-methyl-3-nitropyridinium salts
  作者：M. A. Yurovskaya、A. V. Karchava、A. Z. Afanas'ev、Yu. G. Bundel'

  DOI：10.1007/bf00766999

  日期：1992.4
• Gromov, S. P.; Bundel', Yu. G., Doklady Chemistry, 1985, vol. 281, p. 93 - 95
  作者：Gromov, S. P.、Bundel', Yu. G.

  DOI：——

  日期：——
• Synthesis of indoles from pyridinium compounds 10. Influence of solvents on process of indolization of 3-intropyridinium cations by the action of the N-methylimine of methyl ethyl ketone
  作者：M. A. Yurovskaya、A. V. Karchava、Yu. G. Bundel'

  DOI：10.1007/bf00531474

  日期：1992.9
• GROMOV, S. P.;BUNDEL, YU. G., DOKL. AN CCCP, 1985, 281, N 3, 585-588
  作者：GROMOV, S. P.、BUNDEL, YU. G.

  DOI：——

  日期：——