1-{(1S,4S)-5-[7-(2-chlorophenyl)-8-(4-chlorophenyl)-2-methylpyrazolo[1,5-a][1,3,5]triazine-4-yl]-2,5-diazabicyclo[2.2.1]hept-2-yl}-phenylmethanone | 736993-40-1

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: 1-{(1S,4S)-5-[7-(2-chlorophenyl)-8-(4-chlorophenyl)-2-methylpyrazolo[1,5-a][1,3,5]triazine-4-yl]-2,5-diazabicyclo[2.2.1]hept-2-yl}-phenylmethanone
• 英文别名: 1-{(1S,4S)-5-[7-(2-chlorophenyl)-8-(4-chlorophenyl)-2-methylpyrazolo[1,5-a][1,3,5]triazin-4-yl]-2,5-diazabicyclo[2.2.1]hept-2-yl}-phenylmethanone；[(1S,4S)-5-[7-(2-chlorophenyl)-8-(4-chlorophenyl)-2-methylpyrazolo[1,5-a][1,3,5]triazin-4-yl]-2,5-diazabicyclo[2.2.1]heptan-2-yl]-phenylmethanone
• CAS: 736993-40-1
• 化学式: C₃₀H₂₄Cl₂N₆O
• 分子量: 555.466
• InChiKey: BWZDGRXBMHSGFV-GOTSBHOMSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.7
• 重原子数：
  39
• 可旋转键数：
  4
• 环数：
  7.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  66.6
• 氢给体数：
  0
• 氢受体数：
  5

文献信息

• Cannabinoid receptor ligands and uses thereof
  申请人：Pfizer Inc

  公开号：US20040157839A1

  公开（公告）日：2004-08-12

  Compounds of Formula (I) that act as cannabinoid receptor ligands and their uses in the treatment of diseases linked to the mediation of the cannabinoid receptors in animals are described herein. 1

  化合物的化学式（I），其作为大麻素受体配体并在治疗与动物体内大麻素受体介导相关疾病中的用途被描述在此。
• PYRAZOLO[1,5-A][1,3,5]TRIAZINE DERIVATIVES AS CANNABINOID RECEPTOR LIGANDS
  申请人：Pfizer Products Inc.

  公开号：EP1592691A1

  公开（公告）日：2005-11-09
• US7329658B2
  申请人：——

  公开号：US7329658B2

  公开（公告）日：2008-02-12
• [EN] PYRAZOLO`1,5-A!`1,3,5!TRIAZINE DERIVATIVES AS CANNABINOID RECEPTOR LIGANDS<br/>[FR] DERIVES DE PYRAZOLO[1,5-A][1,3,5]TRIAZINE EN TANT QUE LIGANDS DE RECEPTEUR CANNABINOIDE
  申请人：PFIZER PROD INC

  公开号：WO2004069837A1

  公开（公告）日：2004-08-19

  Compounds of Formula (I) that act as cannabinoid receptor ligands and their uses in the treatment of diseases linked to the mediation of the cannabinoid receptors in animals are described herein.