(S)-2-Benzyloxycarbonylamino-5-({phenylamino-[(Z)-2,4,6-trimethyl-benzenesulfonylimino]-methyl}-amino)-pentanoic acid | 232940-05-5

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: (S)-2-Benzyloxycarbonylamino-5-({phenylamino-[(Z)-2,4,6-trimethyl-benzenesulfonylimino]-methyl}-amino)-pentanoic acid
• CAS: 232940-05-5
• 化学式: C₂₉H₃₄N₄O₆S
• 分子量: 566.678
• InChiKey: XUEKKRCTUHBYNC-VWLOTQADSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.52
• 重原子数：
  40.0
• 可旋转键数：
  11.0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.28
• 拓扑面积：
  146.19
• 氢给体数：
  4.0
• 氢受体数：
  5.0

反应信息

• 作为反应物：
  描述：

  (S)-2-Benzyloxycarbonylamino-5-({phenylamino-[(Z)-2,4,6-trimethyl-benzenesulfonylimino]-methyl}-amino)-pentanoic acid 在 三氟乙酸 作用下， 反应 0.5h， 生成
  参考文献：
  名称：

  A highly effective method for synthesis of Nω-substituted arginines as building blocks for Boc/Fmoc peptide chemistry

  摘要：

  Chemically and optically pure N-omega-substituted arginine derivatives were prepared with high yields in two steps, starting fiom N-alpha-protected ornithine and ArSO2N=C(SMe)(2). The compounds were applied to solid phase peptide synthesis using Boc as well as Fmoc chemistries. (C) 1999 Published by Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4039(99)00767-4
• 作为产物：
  描述：

  Sodium; (S)-5-amino-2-benzyloxycarbonylamino-pentanoate 在 Celite 、 silver nitrate 作用下， 以 四氢呋喃 、 水 、 乙腈 为溶剂， 反应 4.0h， 生成 (S)-2-Benzyloxycarbonylamino-5-({phenylamino-[(Z)-2,4,6-trimethyl-benzenesulfonylimino]-methyl}-amino)-pentanoic acid
  参考文献：
  名称：

  A highly effective method for synthesis of Nω-substituted arginines as building blocks for Boc/Fmoc peptide chemistry

  摘要：

  Chemically and optically pure N-omega-substituted arginine derivatives were prepared with high yields in two steps, starting fiom N-alpha-protected ornithine and ArSO2N=C(SMe)(2). The compounds were applied to solid phase peptide synthesis using Boc as well as Fmoc chemistries. (C) 1999 Published by Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4039(99)00767-4