3,3'-(3,17-diethyl-2,7,13,18-tetramethyl-1,19-dioxo-10,19,21,22,23,24-hexahydro-1H-bilin-8,12-diyl)-di-propionic acid | 79719-28-1

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 四吡咯及其衍生物
• 英文名称: 3,3'-(3,17-diethyl-2,7,13,18-tetramethyl-1,19-dioxo-10,19,21,22,23,24-hexahydro-1H-bilin-8,12-diyl)-di-propionic acid
• 英文别名: 3,3'-(3,17-Diaethyl-2,7,13,18-tetramethyl-1,19-dioxo-10,19,21,22,23,24-hexahydro-1H-bilin-8,12-diyl)-di-propionsaeure；3-[2-[[3-(2-carboxyethyl)-5-[(E)-(3-ethyl-4-methyl-5-oxopyrrol-2-ylidene)methyl]-4-methyl-1H-pyrrol-2-yl]methyl]-5-[(Z)-(3-ethyl-4-methyl-5-oxopyrrol-2-ylidene)methyl]-4-methyl-1H-pyrrol-3-yl]propanoic acid
• CAS: 79719-28-1；83709-07-3；83709-08-4
• 化学式: C₃₃H₄₀N₄O₆
• 分子量: 588.704
• InChiKey: PSUYEWBLPHMDMK-VVCLLGATSA-N

物化性质

• 沸点：
  900.9±65.0 °C(Predicted)
• 密度：
  1.283±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.9
• 重原子数：
  43
• 可旋转键数：
  12
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.39
• 拓扑面积：
  164
• 氢给体数：
  6
• 氢受体数：
  6

反应信息

• 作为产物：
  描述：

  3-(4-methyl-pyrrol-3-yl)-propionic acid 在 盐酸 、 水 、 氢溴酸 、 sodium methylate 、 溶剂黄146 作用下， 生成 3,3'-(3,17-diethyl-2,7,13,18-tetramethyl-1,19-dioxo-10,19,21,22,23,24-hexahydro-1H-bilin-8,12-diyl)-di-propionic acid
  参考文献：
  名称：

  Siedel; Fischer, Hoppe-Seyler's Zeitschrift fur Physiologische Chemie, 1933, vol. 214, p. 145,152, 167

  摘要：

  DOI：

文献信息

• The Activation of Aging Stereotypes in Younger and Older Adults
  作者：A. L. Chasteen、N. Schwarz、D. C. Park

  DOI：10.1093/geronb/57.6.p540

  日期：2002.11.1

  The activation of ageism and aging stereotypes in younger and older adults was investigated by manipulating both the valence and the stereotypicality of trait stimuli. Participants completed a lexical decision task in which the stimulus onset asynchronies (SOAs) between the prime and target stimuli were varied to examine the effects of automatic and controlled processing (300 and 2,000 ms, respectively). Both younger and older adults demonstrated strong stereotype activation for elderly stereotypes but relatively weak activation for young stereotypes. Both younger and older adults also demonstrated a positive bias toward older people, which was not moderated by SOA. These findings suggest that younger and older adults do not differ in their accessibility to aging stereotypes or to their age-based biases, which appear to be positive toward elderly people.