3-(2,2,2-trichloroethoxy)propanoic acid | 100689-47-2

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 3-(2,2,2-trichloroethoxy)propanoic acid
• CAS: 100689-47-2
• 化学式: C₅H₇Cl₃O₃
• 分子量: 221.468
• InChiKey: FDCMFXYJLLICPJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.4
• 重原子数：
  11
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.8
• 拓扑面积：
  46.5
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  3-(2,2,2-trichloroethoxy)propanoic acid 在 草酰氯 作用下， 以 N,N-二甲基甲酰胺 、 苯 为溶剂， 反应 1.5h， 生成 3-(2,2,2-trichloroethoxy)propanoyl chloride
  参考文献：
  名称：

  Bruchins—Mitogenic 3-(Hydroxypropanoyl) Esters of Long Chain Diols from Weevils of the Bruchidae

  摘要：

  Mono- and bis 3-(hydroxypropanoyl) esters of long chain, unsaturated diols have been isolated and identified from two genera of the family Bruchidae, and have been shown to be responsible for the mitogenic activity observed on pea pods resulting from oviposition by the pea weevil, Bruchus pisorum. The mitogenic compounds have been characterized and synthesized. Published by Elsevier Science Ltd.

  DOI：

  10.1016/s0040-4020(00)00650-5
• 作为产物：
  描述：

  methyl 3-(2,2,2-trichloroethoxy)propanoate 在 四丁基溴化铵 、 氢溴酸 作用下， 反应 2.0h， 以88%的产率得到3-(2,2,2-trichloroethoxy)propanoic acid
  参考文献：
  名称：

  Bruchins—Mitogenic 3-(Hydroxypropanoyl) Esters of Long Chain Diols from Weevils of the Bruchidae

  摘要：

  Mono- and bis 3-(hydroxypropanoyl) esters of long chain, unsaturated diols have been isolated and identified from two genera of the family Bruchidae, and have been shown to be responsible for the mitogenic activity observed on pea pods resulting from oviposition by the pea weevil, Bruchus pisorum. The mitogenic compounds have been characterized and synthesized. Published by Elsevier Science Ltd.

  DOI：

  10.1016/s0040-4020(00)00650-5

文献信息

• High pressure high temperature (HPHT) aqueous drilling mud composition and process for preparing the same
  申请人：ISP INVESTMENTS INC.

  公开号：US10113099B2

  公开（公告）日：2018-10-30

  What is described herein is an aqueous high-temperature high-pressure (HTHP) stable drilling mud composition comprising (i) about 20 wt. % to about 80 wt. % of 0-60% w/w brine solution; (ii) about 0.1 wt. % to about 3 wt. % of butylated reaction product of p-cresol and dicyclopentadiene, a polymeric hindered phenol based antioxidant; (iii) about 0.1 wt. % to about 10.0 wt. % of triethanol amine, a chelating agent; (iv) (a) about 0.1 wt. % to about 10 wt. % of rheology modifier (RM); and/or (b) about 0.5 wt. % to about 30 wt. % of fluid loss additive (FLA); (v) about 20 wt. % to about 80 wt. % of weighting agent; (vi) about 0 wt. % to about 20 wt. % of drilling solid; and (vii) about 0 wt. % to about 50 wt % of water.

  本文所述的是一种水基高温高压（HTHP）稳定钻井泥浆组合物，包括(i)约20重量%至约80重量%的0-60% w/w盐水溶液；(ii)约0.1重量%至约3重量%的对甲酚和双环戊二烯的丁基化反应产物，一种基于受阻酚的聚合物抗氧化剂；(iii)约0.1重量%至约10.0 wt. %的三乙醇胺，一种螯合剂；(iv) (a) 约 0.1 wt. %至约 10 wt.(iv) 约 0.1 重量 % 至约 10 重量 % 的流变改性剂 (RM)；和/或 (b) 约 0.5 重量 % 至约 30 重量 % 的流体流失添加剂 (FLA)； (v) 约 20 重量 % 至约 80 重量 % 的增重剂； (vi) 约 0 重量 % 至约 20 重量 % 的钻井固体；以及 (vii) 约 0 重量 % 至约 50 重量 % 的水。
• Eco-friendly non-aqueous antimicrobial composition comprising hinokitiol with 1,3-propanediol and/or sorbitan caprylate
  申请人：ISP INVESTMENTS INC.

  公开号：US10973228B2

  公开（公告）日：2021-04-13

  [Problem] The object is to obtain cosmetics which do not show primary skin irritation or sensitization, and do not impart any unpleasant sensation such as sharp pain or prickly sensation when employed as a cosmetic, with the lowest possible inclusion of preservative/fungicide. [Solution] Antimicrobial low-irritant cosmetics characterized in that they contain one or two or more tropolone derivative(s) and one or two or more polyhydric alcohol(s) in quantities which have an anti-microbial effect and low skin irritancy.

  [问题]目的是获得在用作化妆品时不会对皮肤产生原发性刺激或过敏，也不会产生任何不愉快的感觉，如剧痛或刺痛感，同时防腐剂/杀真菌剂的含量尽可能低的化妆品。 [解]抗菌低刺激性化妆品，其特征在于它们含有一种或两种或两种以上的卫矛酮衍生物和一种或两种或两种以上的多元醇，其数量具有抗菌效果和低皮肤刺激性。
• Microbiocidal anionic sequesterants with polyvalent metal cations for permeability correction process
  申请人：PHILLIPS PETROLEUM COMPANY

  公开号：EP0170893B1

  公开（公告）日：1989-08-30
• AQUEOUS-MISCIBLE OR AQUEOUS-DISPERSIBLE, VOC-FREE BIOCIDAL COMPOSITIONS FOR THE ENHANCED INHIBITION OF GRAM-NEGATIVE BACTERIAL STRAINS, AND METHOD OF PREPARING THE SAME
  申请人：ISP INVESTMENT INC.

  公开号：EP2531034A1

  公开（公告）日：2012-12-12
• A STABLE AND AQUEOUS CONCENTRATED PRESERVATIVE COMPOSITION OF DEHYDROACETIC ACID (DHA) AND METHYLISOTHIAZOLINONE (MIT)
  申请人：ISP Investments Inc.

  公开号：EP2640798A1

  公开（公告）日：2013-09-25