ethyl phenylselanylacetate dichloro-adduct | 309295-43-0

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: ethyl phenylselanylacetate dichloro-adduct
• 英文别名: ethyl 2-[dichloro(phenyl)-λ4-selanyl]acetate
• CAS: 309295-43-0
• 化学式: C₁₀H₁₂Cl₂O₂Se
• 分子量: 314.07
• InChiKey: YJNRBQNIUHXSHP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.38
• 重原子数：
  15.0
• 可旋转键数：
  4.0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.3
• 拓扑面积：
  26.3
• 氢给体数：
  0.0
• 氢受体数：
  2.0

反应信息

• 作为反应物：
  描述：

  ethyl phenylselanylacetate dichloro-adduct 在 吡啶 、 N-氯代丁二酰亚胺 作用下， 以 四氯化碳 、 二氯甲烷 为溶剂， 反应 5.0h， 生成 ethyl α-chloro-α-phenylseleno acetate
  参考文献：
  名称：

  Synthesis and Reactivity of α- and β-Chloro-α-phenylselanyl Esters

  摘要：

  Thermal decomposition of the dichloro-adducts derived from alpha-phenylselanylesters 1, 2 and 4 has been studied. N-Chloro-succinimide treatment of esters 2 was an efficient preparative method for alpha-chloro-alpha-phenylselanylesters 10 and alpha-chloro-alpha,beta-unsaturated esters 11. Some transformations of esters 10 were achieved. alpha,beta-Dichloro-alpha-phenylselanylesters 22 were prepared from beta-chloro-alpha-phenyl selanylesters 5 or by decomposition of the dichloroselenuranes 21 derived from esters 4. (C) 2000 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4020(00)00648-7
• 作为产物：
  描述：

  ethyl 2-(phenylselanyl)acetate 在 磺酰氯 作用下， 以 Petroleum ether 为溶剂， 反应 0.17h， 以92%的产率得到ethyl phenylselanylacetate dichloro-adduct
  参考文献：
  名称：

  Synthesis and Reactivity of α- and β-Chloro-α-phenylselanyl Esters

  摘要：

  Thermal decomposition of the dichloro-adducts derived from alpha-phenylselanylesters 1, 2 and 4 has been studied. N-Chloro-succinimide treatment of esters 2 was an efficient preparative method for alpha-chloro-alpha-phenylselanylesters 10 and alpha-chloro-alpha,beta-unsaturated esters 11. Some transformations of esters 10 were achieved. alpha,beta-Dichloro-alpha-phenylselanylesters 22 were prepared from beta-chloro-alpha-phenyl selanylesters 5 or by decomposition of the dichloroselenuranes 21 derived from esters 4. (C) 2000 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4020(00)00648-7