and electron-withdrawing groups were conveniently synthesized through manganese dioxide (MnO2) oxidation of the corresponding thiazolines. The effect of substitution at the 2- and 4-positions was investigated. The desired thiazoles with aryl or vinyl substitutions at the 2- or 4-position can be obtained in good to excellent yields.
通过
二氧化锰 (
MnO2) 氧化相应的
噻唑啉,可以方便地合成具有给电子和吸电子基团的结构多样的
噻唑。研究了 2 位和 4 位取代的影响。在2-或4-位具有芳基或
乙烯基取代基的所需
噻唑可以良好到极好的产率获得。