tridecanedioic acid monoethyl ester | 13652-77-2

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: tridecanedioic acid monoethyl ester
• 英文别名: Tridecandisaeure-monoaethylester；13-Ethoxy-13-oxotridecanoic acid
• CAS: 13652-77-2
• 化学式: C₁₅H₂₈O₄
• 分子量: 272.385
• InChiKey: AOGHQYQAUPTUGL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.4
• 重原子数：
  19
• 可旋转键数：
  14
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.87
• 拓扑面积：
  63.6
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  tridecanedioic acid monoethyl ester 在 氯化亚砜 作用下， 生成 12-chlorocarbonyl-dodecanoic acid ethyl ester
  参考文献：
  名称：

  叶绿素光敏化不饱和酯形成的单氢过氧化物中氢过氧化物基团的位置

  摘要：

  从油酸甲酯，亚油酸甲酯，亚油酸甲酯和花生四烯酸乙酯的叶绿素光敏氧化分离出单氢过氧化物。通过两种分析由催化氢化形成的饱和羟基酯的方法确定氢过氧化物取代基的位置。降解产物的气液色谱分析和相应的酮酸酯的质谱分析均证明氢过氧化物基团位于最初形成双键一部分的每个碳原子上。

  DOI：

  10.1039/j39660001897
• 作为产物：
  描述：

  alkaline earth salt of/the/ methylsulfuric acid 、 alkaline earth salt of/the/ methylsulfuric acid 在 盐酸 、 二丁醚 作用下， 生成 tridecanedioic acid monoethyl ester
  参考文献：
  名称：

  Jones, Journal of the American Chemical Society, 1947, vol. 69, p. 2352

  摘要：

  DOI：

文献信息

• Molecular Healing of Polymeric Materials, Coatings, Plastics, Elastomers, Composites, Laminates, Adhesives, and Sealants by Active Enzymes
  申请人：McDaniel C. Steven

  公开号：US20100210745A1

  公开（公告）日：2010-08-19

  Disclosed herein are polymeric materials such as a coating, a plastic, a laminate, a composite, an elastomer, an adhesive, or a sealant; a surface treatment such as a textile finish or a wax; a filler for such a polymeric material or a surface treatment that includes an enzyme such as an esterase (e.g., a lipolytic enzyme, a sulfuric ester hydrolase, an organophosphorus compound degradation enzyme), an enzyme (e.g., a lysozyme, a lytic transglycosylase) that degrades a cell wall and/or a cell membrane component, a biocidal or biostatic peotide, and/or a peptidase. Also disclosed herein are methods of altering a material's property such as service life, flexability, or rigidity, by incorporation of an enzyme into a material capable of being chemically crosslinked by the activity of a lipolytic enzyme, a hydrolase, and/or a urease.

  本文公开了一些聚合材料，如涂层、塑料、层压板、复合材料、弹性体、粘合剂或密封剂；一种表面处理，如纺织品涂层或蜡；一种填料，用于这样的聚合材料或表面处理，其中包括一种酶，如酯酶（例如，脂肪水解酶，硫酸酯水解酶，有机磷化合物降解酶），降解细胞壁和/或细胞膜成分的酶（例如，溶菌酶，裂解转糖基酶），生物杀菌或生物静态肽，以及/或肽酶。本文还公开了通过将酶纳入可通过脂肪水解酶、水解酶和/或脲酶的活性交联材料中来改变材料性能，如使用寿命、柔韧性或刚度的方法。
• METHODS FOR PRODUCING DICARBOXYLIC ACIDS
  申请人：Synthetic Genomics, Inc.

  公开号：US20150176041A1

  公开（公告）日：2015-06-25

  The present invention provides methods of producing dicarboxylic acids. The methods involve incubating a fatty acid or hydrocarbon substrate with an enzyme to produce a dicarboxylic acid product. The enzyme acts on the substrate to produce a product that has been both over-oxidized and has undergone cleavage of a C—C bond. In some embodiments the enzymes having these useful characteristics are mutants of a cytochrome P450 enzyme, for example an enzyme of the class CYP102 or a mutant thereof. The invention provides enzymes where these desirable characteristics can be found in a single enzyme, and thus in some embodiments the methods can be performed through the action of a single enzyme.

  本发明提供了生产二羧酸的方法。该方法涉及将脂肪酸或烃基底物与酶孵育以生产二羧酸产物。酶作用于底物以产生经过过氧化和C-C键断裂的产物。在某些实施例中，具有这些有用特性的酶是细胞色素P450酶的突变体，例如CYP102类酶或其突变体。本发明提供了这些理想特性可以在单个酶中找到的酶，因此在某些实施例中，可以通过单个酶的作用来执行该方法。
• Anti-fouling Paints and Coatings
  申请人：Reactive Surfaces LTD

  公开号：US20150191607A1

  公开（公告）日：2015-07-09

  Disclosed herein are polymeric materials such as a coating, a plastic, a laminate, a composite, an elastomer, an adhesive, or a sealant; a surface treatment such as a textile finish or a wax; a filler for such a polymeric material or a surface treatment that includes an enzyme such as an esterase (e.g., a lipolytic enzyme, a sulfuric ester hydrolase, an organophosphorus compound degradation enzyme), an enzyme (e.g., a lysozyme, a lytic transglycosylase) that degrades a cell wall and/or a cell membrane component, a biocidal or biostatic peptide, and/or a peptidase. Also disclosed herein are methods of altering a material's property such as service life, flexability, or rigidity, by incorporation of an enzyme into a material capable of being chemically crosslinked by the activity of a lipolytic enzyme, a hydrolase, and/or a urease.

  本文披露了聚合材料，例如涂层、塑料、层压材料、复合材料、弹性体、粘合剂或密封剂；表面处理，例如纺织品整理或蜡；填充剂，用于这种聚合材料或表面处理，包括酯酶（例如脂肪水解酶、硫酸酯水解酶、有机磷化合物降解酶）的酶，降解细胞壁和/或细胞膜成分的酶（例如溶菌酶、裂解转葡糖苷酶），生物杀菌或生物稳定肽，和/或肽酶。本文还披露了通过将酶并入能够通过脂肪水解酶、水解酶和/或脲酶的活性进行化学交联的材料中，改变材料性能（例如使用寿命、柔韧性或刚度）的方法。
• PROCESS FOR PRODUCING 2-($g(v)-ALKOXYCARBONYLALKANOYL)-4-BUTANOLIDE AND LONG-CHAIN $g(v)-HYDROXY CARBOXYLIC ACID
  申请人：TORAY INDUSTRIES, INC.

  公开号：EP0794182A1

  公开（公告）日：1997-09-10

  2-(ω-alkoxycarbonyl alkanoyl)-4-butanolide can be produced unexpectedly with a high selectivity and yield through condensation reaction of γ-butyrolactone with a highly available, loω-price dicarboxylate as represented by the following general formula:         ROOC(CH2)nCOOR (where n denotes an integer of 7-13, and R denotes an alkyl group or an alkenyl group). Furthermore, a long-chain ω-hydroxycarboxylic acid can be produced by subjecting 2-(ω-alkoxycarbonyl alkanoyl)-4-butanolide to hydrolysis and decarboxylation and reducing the carbonyl groups in the resultant product into methylene groups.

  通过γ-丁内酯与以下通式所代表的高可得性、低ω价二羧酸盐的缩合反应，可以意外地以高选择性和高产率生产出 2-(ω-烷氧羰基烷酰基)-4-丁内酯： ROOC(CH2)nCOOR (其中 n 表示 7-13 的整数，R 表示烷基或烯基）。此外，将 2-(ω-烷氧羰基烷酰基)-4-丁内酯进行水解和脱羧反应，并将所得产物中的羰基还原成亚甲基，可制得长链ω-羟基羧酸。
• SPIROIMIDAZOLONE DERIVATIVE
  申请人：Chugai Seiyaku Kabushiki Kaisha

  公开号：EP2433940A1

  公开（公告）日：2012-03-28

  The present invention relates to a compound represented by the following formula (1): wherein W, X, Y, R1, R2, R33, R34, m and n are as defined in the claims, or a pharmacologically acceptable salt thereof.

  本发明涉及下式（1）所代表的化合物： 其中 W、X、Y、R1、R2、R33、R34、m 和 n 如权利要求中定义，或其药理上可接受的盐。