4-烯丙基苯甲酰胺 | 104699-51-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: 4-烯丙基苯甲酰胺
• 英文名称: 4-allylbenzamide
• 英文别名: 4-prop-2-enylbenzamide
• CAS: 104699-51-6
• 化学式: C₁₀H₁₁NO
• 分子量: 161.203
• InChiKey: CZQKVJRBIQSDMF-UHFFFAOYSA-N

物化性质

• 熔点：
  137-139 °C
• 沸点：
  297.0±19.0 °C(Predicted)
• 密度：
  1.056±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1.9
• 重原子数：
  12
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.1
• 拓扑面积：
  43.1
• 氢给体数：
  1
• 氢受体数：
  1

安全信息

• 海关编码：
  2924299090

反应信息

• 作为产物：
  描述：

  乙酸烯丙酯 、 对溴苯甲胺 在 (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride 六正丁基二锡 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 反应 0.5h， 以86%的产率得到4-烯丙基苯甲酰胺
  参考文献：
  名称：

  钯催化的交叉偶联反应：芳基溴化物与乙酸烯丙酯的直接烯丙基化

  摘要：

  在六正丁基二锡存在下，各种芳基溴化物与乙酸烯丙酯进行钯催化的交叉偶联反应，以很高的收率得到烯丙基化的产物。

  DOI：

  10.1016/s0040-4039(00)99026-9

文献信息

• Cobalt-Catalyzed Direct Electrochemical Cross-Coupling between Aryl or Heteroaryl Halides and Allylic Acetates or Carbonates
  作者：Paulo Gomes、Corinne Gosmini、Jacques Périchon

  DOI：10.1021/jo026421b

  日期：2003.2.1

  The electroreduction of a mixture of functionalized aromatic or heteroaromatic bromides or chlorides and allylic compounds such as acetates or carbonates in an electrochemical cell fitted with a sacrificial iron anode affords, in the presence of cobalt halide associated with pyridine as ligand in acetonitrile or DMF, the corresponding coupling product in good yields.

  在配有牺牲性铁阳极的电化学电池中，将功能化的芳族或杂芳族溴化物或氯化物与烯丙基化合物（如乙酸盐或碳酸盐）的混合物进行电还原，可在乙腈或DMF中与吡啶结合的卤化钴与配体结合时，得到相应的偶联产物，收率很高。
• Polymers of carbon monoxide with olefinically unsaturated compounds
  申请人：SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V.

  公开号：EP0501586A2

  公开（公告）日：1992-09-02

  Polymers of carbon monoxide with one or more olefinically unsaturated compounds, which a) can be prepared by polymerization of carbon monoxide with one or more compounds of the general formula CH₂=CH-R⁶-R⁷ in which R⁷ represents an optionally substituted phenyl group which, with one of the carbon atoms of its aromatic ring, is connected to a divalent aliphatic hydrocarbylene bridging group R⁶ containing at least one carbon atom in the bridge, and, optionally, in addition with one or more olefinically unsaturated aliphatic compounds, b) possess a linear structure, and in which c) the units from carbon monoxide and the units from the olefinically unsaturated compounds are present in a substantially alternating arrangement.

  一氧化碳与一种或多种烯烃不饱和化合物的聚合物，其中 a) 可通过一氧化碳与一种或多种通式为 CH₂=CH-R⁶-R⁷ 的化合物聚合制备，其中 R⁷ 代表任选取代的苯基，该苯基与其芳香环的一个碳原子连接到二价脂肪族烃桥基 R⁶ 上，桥基中至少含有一个碳原子，此外还可任选与一种或多种烯烃不饱和脂肪族化合物聚合、 b) 具有线性结构，其中 c) 来自一氧化碳的单元和来自烯烃不饱和化合物的单元基本上交替排列。
• Liquid dye formulations in non-petroleum based solvent systems
  申请人：Sunbelt Corporation

  公开号：EP2065459A2

  公开（公告）日：2009-06-03

  A dye formulation is disclosed that includes a vegetable oil ester based solvents that have carbon chain lengths of C-1 to C-18, a solvent dye that is a true liquid dye dissolved in the vegetable oil ester for imparting color to the dye formulation, and reduced sulfur levels in commercially available dye formulations as compared to those in hydrocarbon based solvent systems. Sulfur content is typically reduced to 2-3 percent of dye formulations in hydrocarbon based solvents. The formulations are particularly useful for tagging petroleum substrates as well as writing instrument and ink jet formulations.

  本发明公开了一种染料配方，其中包括碳链长度为 C-1 至 C-18 的植物油酯基溶剂、溶解在植物油酯中的真正液体染料溶剂染料（用于给染料配方着色），以及与烃基溶剂系统中的染料配方相比，降低了市售染料配方中的硫含量。 与烃基溶剂中的染料配方相比，硫含量通常降低到 2-3%。 这些配方尤其适用于标记石油基材以及书写工具和喷墨配方。
• Selective Inhibitors of the Polo-Like Kinase 1 Polo-Box Domain
  申请人：UNIVERSITY OF SOUTH CAROLINA

  公开号：US20190269784A1

  公开（公告）日：2019-09-05

  Inhibitors that are specific for the PBD domain of the PLK1 protein are described. The inhibitors include fragment ligated inhibitors that include one or more amino acids of a starting peptide upon which the inhibitors are based and also include non-peptidic inhibitors. The inhibitors include a benzoic acid-based derivative that mimics the structure activity relationship of amino acid residues of known peptide inhibitors. The inhibitors exhibit high selectivity for the PLK1 isotype.
• US6869951B1
  申请人：——

  公开号：US6869951B1

  公开（公告）日：2005-03-22