| 1383547-15-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 菲及其衍生物
• CAS: 1383547-15-6
• 化学式: C₇₄H₂₀O₂
• 分子量: 940.972
• InChiKey: MMFLLTDKJIFZDF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  20.12
• 重原子数：
  76.0
• 可旋转键数：
  8.0
• 环数：
  33.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  26.3
• 氢给体数：
  0.0
• 氢受体数：
  2.0

反应信息

• 作为反应物：
  描述：

  吗啉 、 在 氧气 、 copper(ll) bromide 作用下， 以 N,N-二甲基甲酰胺 、 邻二氯苯 为溶剂， 反应 13.0h， 以72%的产率得到1-(morpholino)-4-[4-(pentyloxycarbonyl)benzyl]-1,4-dihydro[60]fullerene
  参考文献：
  名称：

  Cu-Catalyzed C–H Amination of Hydrofullerenes Leading to 1,4-Difunctionalized Fullerenes

  摘要：

  A novel and highly efficient Cu-catalyzed C-H amination of the monofunctionalized hydrofullerenes for the synthesis of 1,4-difunctional fullerenes has been reported. A new series of 1,4-fullerene derivatives having various monoamine addends were synthesized in good to high yields under mild reaction conditions. The controlled experiments revealed that the reaction proceeds through the formation of a fullerene monoradical as a key intermediate followed by coupling with an amine radical.

  DOI：

  10.1021/ol403573r

文献信息

• NaOH-Catalyzed Dimerization of Monofunctionalized Hydrofullerenes: Transition-Metal-Free, General, and Efficient Synthesis of Single-Bonded [60]Fullerene Dimers
  作者：Shirong Lu、Tienan Jin、Ming Bao、Yoshinori Yamamoto

  DOI：10.1021/ol301435m

  日期：2012.7.6

  NaOH-catalyzed homo- and cross-dimerizations of monofunctionalized hydrofullerenes are reported. Various single-bonded fullerene dimers were synthesized under mild reaction conditions with remarkably high yields. The use of a NaOH catalyst combined with tetrahydrofuran as a cosolvent under an air atmosphere is critical in achieving highly efficient catalytic dimerization.

  据报道，空前的，无过渡金属的NaOH催化的单官能化氢富勒烯的均二和交叉二聚反应。在温和的反应条件下以高产率合成了各种单键富勒烯二聚体。在空气气氛下使用与四氢呋喃结合的NaOH催化剂作为助溶剂对于实现高效催化二聚至关重要。