2-hydroxy-6-methyl-9,10-dihydrophenanthrene | 269392-07-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 菲及其衍生物
• 英文名称: 2-hydroxy-6-methyl-9,10-dihydrophenanthrene
• 英文别名: 9,10-Dihydro-6-methyl-2-phenanthrenol；6-methyl-9,10-dihydrophenanthren-2-ol
• CAS: 269392-07-6
• 化学式: C₁₅H₁₄O
• 分子量: 210.276
• InChiKey: TWAMMCGKEBREHV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.9
• 重原子数：
  16
• 可旋转键数：
  0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  2-methoxy-6-methyl-9,10-dihydrophenanthrene 在 三溴化硼 作用下， 以 二氯甲烷 为溶剂， 生成 2-hydroxy-6-methyl-9,10-dihydrophenanthrene
  参考文献：
  名称：

  摘要：

  9,10-Dihydrophenanthrenes and phenanthrenes, mimics of natural compounds with strong antialgal activity, have been synthesized through cross-coupling of 1-(2-iodo-5-methoxy)-phenylethanol with variously substituted iodobenzenes. The synthetic compounds, bearing a hydroxyl or a methoxyl group at C-2 and a methyl in the C ring, were tested against the green alga Selenastrum capricornutum. All compounds, except 2-methoxy-7-methylphenanthrene, caused inhibition of algal growth by more than 70% at 10(-4) M, and many of them retained this strong activity at 10(-5) M.

  DOI：

  10.1023/a:1005463802388