bis-[2-(4-methyl-phenylamino)-4-phenyl-thiazol-5-yl]-methanone | 952615-12-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: bis-[2-(4-methyl-phenylamino)-4-phenyl-thiazol-5-yl]-methanone
• 英文别名: Bis[2-(4-methylanilino)-4-phenyl-1,3-thiazol-5-yl]methanone
• CAS: 952615-12-2
• 化学式: C₃₃H₂₆N₄OS₂
• 分子量: 558.728
• InChiKey: GPCZBZFJIFTQKG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  9.8
• 重原子数：
  40
• 可旋转键数：
  8
• 环数：
  6.0
• sp3杂化的碳原子比例：
  0.06
• 拓扑面积：
  123
• 氢给体数：
  2
• 氢受体数：
  7

文献信息

• THIAZOLE AND THIOPHENE ANALOGUES, AND THEIR USE IN TREATING AUTOIMMUNE DISEASES AND CANCERS
  申请人：Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College

  公开号：EP2007393B1

  公开（公告）日：2013-08-21
• Thiazole and Thiophene Analogues, and Their Use in Treating Autoimmune Diseases and Cancers
  申请人：Giordano Anthony

  公开号：US20090306073A1

  公开（公告）日：2009-12-10

  Thiazole and thiophene compounds are disclosed having utility in treating inflammatory conditions, immunoinflammatory conditions, autoimmune diseases, and cancers. Methods for the synthesis of these compounds are also disclosed.
• US8217037B2
  申请人：——

  公开号：US8217037B2

  公开（公告）日：2012-07-10
• US8829014B2
  申请人：——

  公开号：US8829014B2

  公开（公告）日：2014-09-09