4-(2,2'-bipyridin-4-yloxy)phenol | 1383804-07-6

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: 4-(2,2'-bipyridin-4-yloxy)phenol
• 英文别名: 4-(2-Pyridin-2-ylpyridin-4-yl)oxyphenol
• CAS: 1383804-07-6
• 化学式: C₁₆H₁₂N₂O₂
• 分子量: 264.283
• InChiKey: FLQRKMVNVSVHOG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.7
• 重原子数：
  20
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  55.2
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  4-(2,2'-bipyridin-4-yloxy)phenol 、 顺-双(2,2-二吡啶)二氯化钌(II) 水合物 以 乙醇 为溶剂， 以88%的产率得到Ru(2,2'-bipyridine)2[4-(2,2'-bipyridin-4-yloxy)phenol]Cl2
  参考文献：
  名称：

  Ruthenium(II) complex-based fluorescent sensor for peroxynitrite

  摘要：

  We have developed a new ruthenium complex, Ru(bpy)(2)[4-(2,2'-bipyridin-4-yloxy)phenol]Cl-2 (RuL), as a fluorescent sensor to detect peroxynitrite (ONOO-). The results showed that the addition of ONOO- to the aqueous solution of RuL would result in distinct fluorescence quenching at 600 nm. Rid. exhibits a good selectivity for ONOO- over other reactive oxygen species (ROS) and reactive nitrite species (RNS), and the reaction time is less than 1.5s. The sensing mechanism is proposed as the oxidative O-dealkylation reaction. (C) 2012 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.saa.2012.03.067
• 作为产物：
  描述：

  4,4'-二甲氧基-2,2'-联吡啶 在 氢溴酸 、 三溴化磷 、 potassium carbonate 、 溶剂黄146 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 反应 11.17h， 生成 4-(2,2'-bipyridin-4-yloxy)phenol
  参考文献：
  名称：

  Ruthenium(II) complex-based fluorescent sensor for peroxynitrite

  摘要：

  We have developed a new ruthenium complex, Ru(bpy)(2)[4-(2,2'-bipyridin-4-yloxy)phenol]Cl-2 (RuL), as a fluorescent sensor to detect peroxynitrite (ONOO-). The results showed that the addition of ONOO- to the aqueous solution of RuL would result in distinct fluorescence quenching at 600 nm. Rid. exhibits a good selectivity for ONOO- over other reactive oxygen species (ROS) and reactive nitrite species (RNS), and the reaction time is less than 1.5s. The sensing mechanism is proposed as the oxidative O-dealkylation reaction. (C) 2012 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.saa.2012.03.067