6-(3-butyl-1,2,4-oxadiazol-5-yl)-2-(3-(trifluoromethyl)phenyl)pyrimidine-4,5-diol | 1407170-96-0

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: 6-(3-butyl-1,2,4-oxadiazol-5-yl)-2-(3-(trifluoromethyl)phenyl)pyrimidine-4,5-diol
• 英文别名: 4-(3-butyl-1,2,4-oxadiazol-5-yl)-5-hydroxy-2-[3-(trifluoromethyl)phenyl]-1H-pyrimidin-6-one
• CAS: 1407170-96-0
• 化学式: C₁₇H₁₅F₃N₄O₃
• 分子量: 380.326
• InChiKey: NDGXBDOUCSTJGR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.3
• 重原子数：
  27
• 可旋转键数：
  5
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.29
• 拓扑面积：
  101
• 氢给体数：
  2
• 氢受体数：
  9

文献信息

• PYRIMIDINONE COMPOUNDS AND METHODS FOR PREVENTING AND TREATING INFLUENZA
  申请人：Webb Thomas R.

  公开号：US20140079666A1

  公开（公告）日：2014-03-20

  In one aspect, the invention relates to novel, broad-spectrum anti-viral, pyrimidinone compounds, methods of use, compositions and kits useful in treating and/or preventing influenza. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
• US9328075B2
  申请人：——

  公开号：US9328075B2

  公开（公告）日：2016-05-03