3-(4-nitrophenyl)-1-phenyl-3-(butylthio)propan-1-one | 706816-61-7

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 直链 1,3-二芳基丙烷
• 英文名称: 3-(4-nitrophenyl)-1-phenyl-3-(butylthio)propan-1-one
• 英文别名: 3-(Butylsulfanyl)-3-(4-nitrophenyl)-1-phenylpropan-1-one；3-butylsulfanyl-3-(4-nitrophenyl)-1-phenylpropan-1-one
• CAS: 706816-61-7
• 化学式: C₁₉H₂₁NO₃S
• 分子量: 343.447
• InChiKey: QNZKZDMVWKDZSQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.8
• 重原子数：
  24
• 可旋转键数：
  8
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.32
• 拓扑面积：
  88.2
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  丁硫醇 、 (E)-3-(4-nitrophenyl)-1-phenylprop-2-en-1-one 在 1-甲基-3-戊基溴化咪唑 作用下， 反应 1.5h， 以93%的产率得到3-(4-nitrophenyl)-1-phenyl-3-(butylthio)propan-1-one
  参考文献：
  名称：

  Catalysis by ionic liquid: a simple, green and efficient procedure for the Michael addition of thiols and thiophosphate to conjugated alkenes in ionic liquid, [pmIm]Br

  摘要：

  A room temperature ionic liquid, 1-pentyl-3-methylimidazolium bromide, [pmIm]Br efficiently catalyzes Michael addition of thiols and diethyl dithiophosphate to a variety of conjugated alkenes such as alpha,beta-unsaturated carbonyl compounds, carboxylic esters, nitriles and chalcones without requiring any other organic solvent and catalyst. The ionic liquid can be recycled for subsequent reactions without any appreciable loss of efficiency. (C) 2004 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2004.03.052

文献信息

• Catalysis by ionic liquid: a simple, green and efficient procedure for the Michael addition of thiols and thiophosphate to conjugated alkenes in ionic liquid, [pmIm]Br
  作者：Brindaban C Ranu、Suvendu S Dey

  DOI：10.1016/j.tet.2004.03.052

  日期：2004.5

  A room temperature ionic liquid, 1-pentyl-3-methylimidazolium bromide, [pmIm]Br efficiently catalyzes Michael addition of thiols and diethyl dithiophosphate to a variety of conjugated alkenes such as alpha,beta-unsaturated carbonyl compounds, carboxylic esters, nitriles and chalcones without requiring any other organic solvent and catalyst. The ionic liquid can be recycled for subsequent reactions without any appreciable loss of efficiency. (C) 2004 Elsevier Ltd. All rights reserved.