1-Propyl-3,5-dimethyl-1,2,4-triazol | 73479-13-7

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: 1-Propyl-3,5-dimethyl-1,2,4-triazol
• 英文别名: 3,5-dimethyl-1-propyl-1H-[1,2,4]triazole；3,5-Dimethyl-1-propyl-1,2,4-triazole
• CAS: 73479-13-7
• 化学式: C₇H₁₃N₃
• 分子量: 139.2
• InChiKey: HQDZDVGFESXATK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.6
• 重原子数：
  10
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.71
• 拓扑面积：
  30.7
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• PIPERAZINE COMPOUND CAPABLE OF INHIBITING PROSTAGLANDIN D SYNTHASE
  申请人：Urade Yoshihiro

  公开号：US20110319413A1

  公开（公告）日：2011-12-29

  This invention relates to a piperazine compound represented by Formula (I), wherein R 1 is C 1-6 alkyl; R 2 is hydroxy, C 1-6 alkyl that may have one or more substituents, —(C═O)—N(R 3 )(R 4 ), or —(C═O)—OR 5 ; R 3 and R 4 are the same or different, and each represents hydrogen or C 1-6 alkyl that may have one or more substituents, or R 3 and R 4 , taken together with a nitrogen atom to which R 3 and R 4 are attached, may form a saturated heterocyclic group; R 5 is hydrogen or C 1-6 alkyl that may have one or more substituents; and n is 1 or 2; or a salt thereof.

  该发明涉及一种由式（I）表示的哌嗪化合物，其中R1是C1-6烷基；R2是羟基，可能具有一个或多个取代基的C1-6烷基，—(C═O)—N(R3)(R4)，或—(C═O)—OR5；R3和R4相同或不同，每个代表氢或可能具有一个或多个取代基的C1-6烷基，或R3和R4与R3和R4连接的氮原子一起，可能形成饱和杂环基团；R5是氢或可能具有一个或多个取代基的C1-6烷基；n为1或2；或其盐。
• BENZAMIDE AND NICOTINAMIDE COMPOUNDS AND METHODS OF USING SAME
  申请人：ONCOTARTIS, INC.

  公开号：US20160347748A1

  公开（公告）日：2016-12-01

  The present disclosure provides benzamide and nicotinamide compounds and pharmaceutical uses of the compounds. The compounds can be used to treat, for example, cancers such hematopoietic cancers (e.g., leukemia). The preferred compounds of the invention contain a phenylethynyl moiety as well as an amine-based heterocyclyl or heteroaryl moiety attached to the benzamide or nicotinamide compound.
• US8865714B2
  申请人：——

  公开号：US8865714B2

  公开（公告）日：2014-10-21
• US9062035B2
  申请人：——

  公开号：US9062035B2

  公开（公告）日：2015-06-23