taxifolin*γ-CD | 1310728-97-2

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 黄酮类化合物
• 英文名称: taxifolin*γ-CD
• CAS: 1310728-97-2
• 化学式: C₁₅H₁₂O₇*C₄₈H₈₀O₄₀
• 分子量: 1601.4
• InChiKey: LICQITZJZLPGLJ-CVLKVTJASA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -16.22
• 重原子数：
  110.0
• 可旋转键数：
  9.0
• 环数：
  33.0
• sp3杂化的碳原子比例：
  0.79
• 拓扑面积：
  760.65
• 氢给体数：
  29.0
• 氢受体数：
  47.0

反应信息

• 作为产物：
  描述：

  γ-环糊精 、 花旗松素 以 乙醇 、 水 为溶剂， 反应 120.0h， 以82%的产率得到taxifolin*γ-CD
  参考文献：
  名称：

  Host–guest system of taxifolin and native cyclodextrin or its derivative: Preparation, characterization, inclusion mode, and solubilization

  摘要：

  The inclusion complexation behavior, characterization and binding ability of taxifolin with native cyclodextrin (alpha-, beta-, or gamma-CD) and its derivative hydroxypropyl-beta-cyclodextrin (HP beta CD) were investigated in both solution and the solid state by means of XRD, DSC, SEM, H-1 and 2D NMR and UV-vis spectroscopy. The results showed that the water solubility and thermal stability of taxifolin were obviously increased in the inclusion complex with cyclodextrins. This satisfactory water solubility and high thermal stability of the taxifolin/CD complexes will be potentially useful for their application as herbal medicines or healthcare products. (C) 2011 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.carbpol.2011.03.029