4-甲氧基-6-甲基-2(1H)-嘧啶酮 | 61000-87-1

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二嗪类
• 中文名称: 4-甲氧基-6-甲基-2(1H)-嘧啶酮
• 英文名称: 4-methoxy-6-methyl-1H-pyrimidin-2-one
• 英文别名: 4-Methoxy-6-methyl-1H-pyrimidin-2-on；4-Methoxy-6-methylpyrimidin-2-ol；4-methoxy-6-methyl-1H-pyrimidin-2-one
• CAS: 61000-87-1
• 化学式: C₆H₈N₂O₂
• mdl: MFCD28053449
• 分子量: 140.142
• InChiKey: NOKMBWMSYJRBSE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.1
• 重原子数：
  10
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.333
• 拓扑面积：
  50.7
• 氢给体数：
  1
• 氢受体数：
  2

安全信息

• 海关编码：
  2933599090

反应信息

• 作为反应物：
  描述：

  4-甲氧基-6-甲基-2(1H)-嘧啶酮 生成 6-甲基尿嘧啶
  参考文献：
  名称：

  McOmie et al., Journal of the Chemical Society, 1957, p. 1830,1832

  摘要：

  DOI：
• 作为产物：
  描述：

  6-甲基-4-甲氧基-2-甲硫基嘧啶 在 sodium hydroxide 、 水 、 氯 作用下， 生成 4-甲氧基-6-甲基-2(1H)-嘧啶酮
  参考文献：
  名称：

  McOmie et al., Journal of the Chemical Society, 1957, p. 1830,1832

  摘要：

  DOI：

文献信息

• Pyrazinecarboxamide Derivatives and Plant Disease Controlling Agents Containing the Same
  申请人：Oda Masatsugu

  公开号：US20090233934A1

  公开（公告）日：2009-09-17

  The present invention provides the compounds represented by the general formula (I): [wherein X is a halogen atom or an (C 1 -C 3 )alkyl group which may be substituted with a halogen atom(s); Y is a hydrogen or halogen atom, or a cyano, a (C 1 -C 3 )alkyl or (C 1 -C 3 )alkoxy group; R is a hydrogen or halogen atom, a cyano group, or a (C 1 -C 6 )alkyl, (C 2 -C 6 )alkenyl group, (C 2 -C 6 )alkynyl, (C 1 -C 6 )alkoxy, (C 2 -C 6 )alkenyloxy, (C 2 -C 6 )alkynyloxy, (C 1 -C 6 )alkylthio, (C 1 -C 6 )alkylsulfinyl or (C 1 -C 6 )alkylsulfonyl group which may be substituted with a halogen atom(s), a (C 1 -C 6 )alkoxycarbonyl group, a (C 1 -C 6 )alkoxyimino(C 1 -C 3 )alkyl group, a tri(C 1 -C 10 )alkylsilyl group, or a phenyl, phenoxy, pyridyloxy or pyrimidyloxy group which may be substituted with a substituent(s); n is an integer of 1 to 5], which compounds cause reduced loads of deleterious, harmful effects to the earth environment, and exhibit a widened controlling spectrum at lowered chemical application rates, thereby finding useful application as a plant disease controlling agent for agricultural and horticultural uses.

  本发明提供了一种由一般式(I)表示的化合物：[其中，X是卤素原子或(C1-C3)烷基，可以用卤素原子取代；Y是氢原子或卤素原子，或氰基，(C1-C3)烷基或(C1-C3)烷氧基；R是氢原子或卤素原子，氰基，(C1-C6)烷基，(C2-C6)烯基，(C2-C6)炔基，(C1-C6)烷氧基，(C2-C6)烯氧基，(C2-C6)炔氧基，(C1-C6)烷硫基，(C1-C6)烷基亚砜基或(C1-C6)烷基磺酰基，可以用卤素原子取代，(C1-C6)烷氧羰基，(C1-C6)烷氧亚胺基(C1-C3)烷基，三(C1-C10)烷基硅烷基，或苯基，苯氧基，吡啶氧基或嘧啶氧基，可以用取代基取代；n是1到5的整数]，这些化合物可以减少对地球环境的有害影响，并在降低化学施用率的情况下展现出扩大的控制光谱，因此可以作为一种农业和园艺用植物病害防治剂的有用应用。
• N-2-(Hetero)Arylethylcarboxamide Derivative, and Pest-Controlling Agent Comprising the Same
  申请人：Oda Masatsugu

  公开号：US20110136831A1

  公开（公告）日：2011-06-09

  An N-2-(hetero)arylethylcarboxamide derivative represented by the formula (I) wherein R 1 and R 2 are each independently a hydrogen atom etc., R 3 and R 4 are each independently a hydrogen atom etc., each Y is independently a halogen atom; a (C 1 -C 6 )alkyl group optionally substituted by halogen atom(s) etc., n is an integer of 1 to 5, A is a specific substituted cyclic group, E is C—H; C—Y (Y is as defined above); or a nitrogen atom, a salt thereof, and a pest controlling agent containing the derivative or salt as an active ingredient show superior performance as compared to the prior art technique, and are is useful particularly as plant disease controlling agents or nematocides having a broad control spectrum at a low dose.

  一种N-2-(杂)芳基乙基羧酰胺衍生物，其化学式表示为(I)，其中R1和R2分别独立地表示氢原子等，R3和R4分别独立地表示氢原子等，每个Y独立地表示卤原子；一种(C1-C6)烷基，该烷基可选择地被卤原子等取代等，n为1至5的整数，A是一种特定的取代环状基团，E为C—H；C—Y（其中Y如上所定义）；或氮原子，其盐，以及含有该衍生物或盐作为活性成分的杀虫剂与先前技术相比表现出卓越性能，并且特别适用于具有广泛控制光谱的植物病害控制剂或线虫剂，剂量低。
• Ochiai; Yamanaka, Pharmaceutical Bulletin, 1955, vol. 3, p. 175,176
  作者：Ochiai、Yamanaka

  DOI：——

  日期：——
• Synthesis of 6-methyluracil-5-sulfonyl chloride
  作者：I. P. Pogorelova、V. D. Orlov、A. D. Isak

  DOI：10.1134/s1070427206040240

  日期：2006.4

  Sulfochlorination of 6-methyluracil with chlorosulfonic acid in the presence of thionyl chloride was studied. The lactam-lactim tautomerism of 6-methyluracil was considered. Ways to increase the yield of the sulfonyl chloride were suggested. The mechanism of the effect exerted by thionyl chloride additions was discussed.
• ENDOPARASITE CONTROL AGENT
  申请人：Kita Kiyoshi

  公开号：US20140088157A1

  公开（公告）日：2014-03-27

  Provided are an endoparasite control agent comprising a carboxamide derivative represented by the general formula (I): or a salt thereof as an active ingredient, and a method for controlling endoparasites, comprising orally or parenterally administering the endoparasite control agent.