5,5'-bis(1-hydroxyethyl)-2,2',3,3'-tetramethoxybiphenyl | 28132-13-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 5,5'-bis(1-hydroxyethyl)-2,2',3,3'-tetramethoxybiphenyl
• 英文别名: 5,5'-Bishydroxymethyl-2,2',3,3'-tetramethoxybiphenyl；[5'-(Hydroxymethyl)-2',3',5,6-tetramethoxy-1,1'-biphenyl-3-yl]methanol；[3-[5-(hydroxymethyl)-2,3-dimethoxyphenyl]-4,5-dimethoxyphenyl]methanol
• CAS: 28132-13-0
• 化学式: C₁₈H₂₂O₆
• mdl: MFCD03448878
• 分子量: 334.369
• InChiKey: JTWMBPWZXQWMPH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.7
• 重原子数：
  24
• 可旋转键数：
  7
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  77.4
• 氢给体数：
  2
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  5,5'-bis(1-hydroxyethyl)-2,2',3,3'-tetramethoxybiphenyl 在 吡啶 、 sodium hydroxide 、 氯化亚砜 、 硫酸 、 硝酸 、 溶剂黄146 作用下， 以 二甲基亚砜 为溶剂， 生成
  参考文献：
  名称：

  与黑色素化学有关的研究。第七部分 尝试从3,4-二羟基苯乙胺和3,4-二羟基苯基丙氨酸合成黑色素时，可能的中间体合成羟基化的二吲哚基，联苯和二氢吲哚-2-羧酸

  摘要：

  描述了5,5'-，6,6'-和5,6'-双-（2-氨基乙基）-2,2'，3,3'-四羟基联苯，2,4-双-（3 1,4-二羟基苯基）丁烷-1,3-二胺和2,3-双-（3,4-二羟基苯基）丁烷-1,4-二胺二盐酸盐，5,5'-，6,6'-和5 ，6′-双-（2-氨基-2-羧乙基）-2，2′，3，3′-四羟基联苯和5，6-二羟基二氢吲哚-2-羧酸。

  DOI：

  10.1039/j39700000865
• 作为产物：
  描述：

  6,6-二羟基-5,5-二甲氧基-(1,1-联苯-基)-3,3-二甲醛 在 sodium hydroxide 、 sodium tetrahydroborate 作用下， 生成 5,5'-bis(1-hydroxyethyl)-2,2',3,3'-tetramethoxybiphenyl
  参考文献：
  名称：

  与黑色素化学有关的研究。第七部分 尝试从3,4-二羟基苯乙胺和3,4-二羟基苯基丙氨酸合成黑色素时，可能的中间体合成羟基化的二吲哚基，联苯和二氢吲哚-2-羧酸

  摘要：

  描述了5,5'-，6,6'-和5,6'-双-（2-氨基乙基）-2,2'，3,3'-四羟基联苯，2,4-双-（3 1,4-二羟基苯基）丁烷-1,3-二胺和2,3-双-（3,4-二羟基苯基）丁烷-1,4-二胺二盐酸盐，5,5'-，6,6'-和5 ，6′-双-（2-氨基-2-羧乙基）-2，2′，3，3′-四羟基联苯和5，6-二羟基二氢吲哚-2-羧酸。

  DOI：

  10.1039/j39700000865

文献信息

• Process for preparing biphenyl compounds
  申请人：UNIVERSITÉ DE BORDEAUX

  公开号：US10155969B2

  公开（公告）日：2018-12-18

  The present invention relates to a process for preparing a compound having the formula (I), said process comprising the following steps: a) the addition of an oxygen source into a solution of a compound of formula (II), in a water-miscible solvent, b) the addition of a laccase in the solution obtained after step a); and c) the possible recovering of the compound of formula (I) thus obtained.

  本发明涉及一种制备具有化学式(I)的化合物的方法，该方法包括以下步骤：a)将氧源加入到具有化学式(II)的化合物的溶液中，溶剂为水溶性溶剂；b)将漆酶加入到步骤a)得到的溶液中；c)可能回收所得到的具有化学式(I)的化合物。
• New phenolic polymers and preparation processes thereof
  申请人：Université de Bordeaux

  公开号：EP3002303A1

  公开（公告）日：2016-04-06

  The present invention concerns the use of a compound having the following formula (I): for the preparation of a polymer. The present invention also concerns the polymers obtained from the polymerization of compound of formula (I), and their processes of preparation.

  本发明涉及具有下式 (I) 的化合物的用途： 用于制备聚合物。 本发明还涉及由式（I）化合物聚合得到的聚合物及其制备工艺。
• Investigation of lignin models of the biphenyl type by X-ray crystallography and NMR spectroscopy
  作者：Gösta Brunow、Pirkko Karhunen、Knut Lundquist、Solveig Olson、Rolf Stomberg

  DOI：10.1007/bf01666186

  日期：1995.1

  Lignin models of the biphenyl type have been synthesized and crystal structures of two of them have been determined. The tetraacetate of 5,5'-bis(hydroxymethyl)-3,3'-dimethoxy-2,2'-biphenyldiol crystallizes in space group P1BAR with a = 11.319(2), b = 12.232(6), c = 9.242(3) angstrom, alpha = 101.66(3)-degrees, beta = 108.14(2)-degrees, gamma = 79.08(2)-degrees and Z = 2. R = 0.036 (2720 observed [I > 3sigma(I)] reflections). The acetate of 5,5'-di-tert-butyl-2',3,3'-trimethoxy-2-biphenylol crystallizes in space group P1BAR with a = 11.972(2), b = 21.621(3), c = 9.834(1) angstrom, alpha = 91.18(1)-degrees, beta = 113.13(1)-degrees, gamma = 98.42(1)-degrees, and Z = 4. R = 0.050 (8129 observed [I > 3sigma(I)] reflections). H-1 NMR and C-13 NMR data for the above-mentioned compounds and a third model, the diacetate of 5,5'-bis(1-hydroxyethyl)-2,2',3,3'-tetramethoxybiphenyl, are reported. Observed signal positions are compared with those calculated on the basis of crystal structure data. The possibilities to obtain structural information about biphenyl structures in lignins from NMR spectra are discussed.
• NEW PROCESS FOR PREPARING BIPHENYL COMPOUNDS
  申请人：UNIVERSITÉ DE BORDEAUX

  公开号：US20170240937A1

  公开（公告）日：2017-08-24

  The present invention relates to a process for preparing a compound having the formula (I), said process comprising the following steps: a) the addition of an oxygen source into a solution of a compound of formula (II), in a water-miscible solvent, b) the addition of a laccase in the solution obtained after step a); and c) the possible recovering of the compound of formula (I) thus obtained.
• NEW PHENOLIC POLYMERS AND PREPARATION PROCESSES THEREOF
  申请人：UNIVERSITÉ DE BORDEAUX

  公开号：US20170260329A1

  公开（公告）日：2017-09-14

  The present invention concerns the use of a compound having the following formula (I), for the preparation of a polymer. The present invention also concerns the polymers obtained from polymerization of compound of formula (I), and their processes of preparation.