2-(2-benzyloxy-5-methoxybenzyl)-1,3-dioxolane | 205433-76-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: 2-(2-benzyloxy-5-methoxybenzyl)-1,3-dioxolane
• 英文别名: 2-[(5-Methoxy-2-phenylmethoxyphenyl)methyl]-1,3-dioxolane
• CAS: 205433-76-7
• 化学式: C₁₈H₂₀O₄
• 分子量: 300.354
• InChiKey: UJARSVRWPOESNE-UHFFFAOYSA-N

物化性质

• 沸点：
  436.7±40.0 °C(Predicted)
• 密度：
  1.165±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.3
• 重原子数：
  22
• 可旋转键数：
  6
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  36.9
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  2-(2-benzyloxy-5-methoxybenzyl)-1,3-dioxolane 在 palladium on activated charcoal 氢气 作用下， 以 乙酸乙酯 为溶剂， 反应 6.0h， 以88%的产率得到2-(1,3-dioxolan-2-ylmethyl)-4-methoxyphenol
  参考文献：
  名称：

  Photochemistry of Substituted 4,4-Dimethoxy-2,5-Cyclohexadienones

  摘要：

  Abstract4,4‐Dimethoxy‐2,5‐cyclohexadienones 9–14 were prepared from the corresponding hydroquinone monomethyl ethers by oxidation with thallium trinitrate in methanol. Irradiation of solutions of 9–13 in methanol with a broad band of UV light centered at 350 nm in a Rayonet reactor afforded 2‐cyclopentenone derivatives 15–19 in moderate to excellent yields, whereas irradiation of 14 in methanol gave phenol 8 along with other unidentified products. Irradiation of 11–14 in benzene yielded substituted phenols. The plausible reaction pathways for the product formation are discussed.

  DOI：

  10.1002/jccs.199800001
• 作为产物：
  描述：

  2-allyl-1-(benzyloxy)-4-methoxybenzene 在 对甲苯磺酸 、 臭氧 作用下， 以 甲醇 、 二氯甲烷 、 苯 为溶剂， 反应 0.2h， 生成 2-(2-benzyloxy-5-methoxybenzyl)-1,3-dioxolane
  参考文献：
  名称：

  Photochemistry of Substituted 4,4-Dimethoxy-2,5-Cyclohexadienones

  摘要：

  Abstract4,4‐Dimethoxy‐2,5‐cyclohexadienones 9–14 were prepared from the corresponding hydroquinone monomethyl ethers by oxidation with thallium trinitrate in methanol. Irradiation of solutions of 9–13 in methanol with a broad band of UV light centered at 350 nm in a Rayonet reactor afforded 2‐cyclopentenone derivatives 15–19 in moderate to excellent yields, whereas irradiation of 14 in methanol gave phenol 8 along with other unidentified products. Irradiation of 11–14 in benzene yielded substituted phenols. The plausible reaction pathways for the product formation are discussed.

  DOI：

  10.1002/jccs.199800001