3-oxo-nonanoic acid (5-acetyl-2-methylsulfanyl-thiazol-4-yl)-amide | 676556-49-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: 3-oxo-nonanoic acid (5-acetyl-2-methylsulfanyl-thiazol-4-yl)-amide
• 英文别名: N-(5-acetyl-2-methylsulfanyl-1,3-thiazol-4-yl)-3-oxononanamide
• CAS: 676556-49-3
• 化学式: C₁₅H₂₂N₂O₃S₂
• 分子量: 342.483
• InChiKey: VUBKBKUONYBAEO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.2
• 重原子数：
  22
• 可旋转键数：
  10
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.6
• 拓扑面积：
  130
• 氢给体数：
  1
• 氢受体数：
  6

文献信息

• Modulation of pathogenicity
  申请人：Ammendola Aldo

  公开号：US20080182878A1

  公开（公告）日：2008-07-31

  The present invention relates to the use of compounds of the general Formula (I): wherein in Formula (I), R is H, alkyl, cycloalkyl, aryl or heteroaryl; R 1 is H, alkyl, cycloalkyl, aryl or heteroaryl; R 2 is H, alkyl, cycloalkyl, aryl or heteroaryl; A 1 and A 2 each independently represent an optionally substituted C 1 -C 20 -alkyl group which may contain one or more group(s) Z, or a monocyclic or polycyclic optionally substituted aromatic or non-aromatic ring system which may contain one or more group(s) X, and in case of a polycyclic ring system, said system contains at least one aromatic ring; Z is selected from the group consisting of S, O, N, NR 4 , CO, CO 2 , CS, SO or SO 2 X is selected from the group consisting of S, O, N; NR 4 , SO or SO 2 ;