(S)-cyclohex-3-en-1-yl methanesulfonate | 290310-93-9

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 有机磺酸及其衍生物
• 英文名称: (S)-cyclohex-3-en-1-yl methanesulfonate
• 英文别名: [(1S)-cyclohex-3-en-1-yl]methyl methanesulfonate
• CAS: 290310-93-9
• 化学式: C₈H₁₄O₃S
• 分子量: 190.263
• InChiKey: DRPKJZBPDGBVJF-MRVPVSSYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.32
• 重原子数：
  12.0
• 可旋转键数：
  3.0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.75
• 拓扑面积：
  43.37
• 氢给体数：
  0.0
• 氢受体数：
  3.0

反应信息

• 作为反应物：
  描述：

  (S)-cyclohex-3-en-1-yl methanesulfonate 在 Raney-Cu 水 作用下， 以 二甲基亚砜 为溶剂， 反应 18.5h， 生成 (1S)-cyclohex-3-eneacetamide
  参考文献：
  名称：

  摘要：

  Cyclic nucreo-delta-amino acids that constitute monomers of a conformationally constrained nucleo-delta-peptide base-pairing system have been prepared. Their synthesis starts with an enantioselectively catalyzed chirogenic Diels-Alder reaction, proceeds via a regioselective epsilon-iodolactamization process, and ends with a regio- as well as diastereoselective introduction of nucleobases through S(N)2-type opening of a transiently formed N-acylaziridine ring. Extensive use of X-ray crystal-structure analysis has been made to support structure assignments.

  DOI：

  10.1002/1522-2675(20000607)83:6<1049::aid-hlca1049>3.0.co;2-1
• 作为产物：
  描述：

  methyl (1S)-cyclohex-3-ene-1-carboxylate 在 lithium aluminium tetrahydride 作用下， 以 四氢呋喃 、 吡啶 为溶剂， 反应 3.5h， 生成 (S)-cyclohex-3-en-1-yl methanesulfonate
  参考文献：
  名称：

  摘要：

  Cyclic nucreo-delta-amino acids that constitute monomers of a conformationally constrained nucleo-delta-peptide base-pairing system have been prepared. Their synthesis starts with an enantioselectively catalyzed chirogenic Diels-Alder reaction, proceeds via a regioselective epsilon-iodolactamization process, and ends with a regio- as well as diastereoselective introduction of nucleobases through S(N)2-type opening of a transiently formed N-acylaziridine ring. Extensive use of X-ray crystal-structure analysis has been made to support structure assignments.

  DOI：

  10.1002/1522-2675(20000607)83:6<1049::aid-hlca1049>3.0.co;2-1