8-Methyl-9-phenyl-guanin | 25477-72-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: 8-Methyl-9-phenyl-guanin
• 英文别名: 2-amino-8-methyl-9-phenyl-1,9-dihydro-purin-6-one；2-amino-8-methyl-9-phenyl-1H-purin-6-one
• CAS: 25477-72-9
• 化学式: C₁₂H₁₁N₅O
• 分子量: 241.252
• InChiKey: BESUPYYPGOCNGN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.9
• 重原子数：
  18
• 可旋转键数：
  1
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.08
• 拓扑面积：
  85.3
• 氢给体数：
  2
• 氢受体数：
  2

文献信息

• HETEROCYCLIC COMPOUND
  申请人：TOHOKU UNIVERSITY

  公开号：US20200163970A1

  公开（公告）日：2020-05-28

  Provided is a novel compound or salt thereof that induces degradation by autophagy of an intracellular molecule. In this compound, a ligand having activity to bind to an intracellular molecule and a structure having activity to induce autophagy of an intracellular molecule are linked via a linker without loss of the activity of the ligand and the structure.