12-bromo-dodecanoic acid dodecylamine | 798557-92-3

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 12-bromo-dodecanoic acid dodecylamine
• 英文别名: 12-Bromo-N-dodecyldodecanamide；12-bromo-N-dodecyldodecanamide
• CAS: 798557-92-3
• 化学式: C₂₄H₄₈BrNO
• 分子量: 446.555
• InChiKey: DOMNZXMXCXBGEU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  10.1
• 重原子数：
  27
• 可旋转键数：
  22
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.96
• 拓扑面积：
  29.1
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  12-bromo-dodecanoic acid dodecylamine 、 11-(2-hydroxyphenoxy)undecanoic acid dodecylamide 在 potassium carbonate 作用下， 以 丙酮 为溶剂， 反应 120.0h， 以67%的产率得到12-[2-(10-dodecylcarbamoyldecyloxy)phenoxy]dodecanoic acid dodecylamide
  参考文献：
  名称：

  Design and STM Investigation of Intramolecular Folding in Self-Assembled Monolayers on the Surface

  摘要：

  The rational design of catechol bis-amides rendered molecular structures that fold into beta-turn mimics at the interface of HOPG and 1-octanol as demonstrated by STM. These self-assembled monolayers provide a prototypical model for linear sequences containing more turn mimics, which will allow for true synthetic surface confined foldamers.

  DOI：

  10.1021/ja046124j
• 作为产物：
  描述：

  12-溴十二烷酸 在 氯化亚砜 、 三乙胺 作用下， 以 二氯甲烷 为溶剂， 反应 14.0h， 生成 12-bromo-dodecanoic acid dodecylamine
  参考文献：
  名称：

  Design and STM Investigation of Intramolecular Folding in Self-Assembled Monolayers on the Surface

  摘要：

  The rational design of catechol bis-amides rendered molecular structures that fold into beta-turn mimics at the interface of HOPG and 1-octanol as demonstrated by STM. These self-assembled monolayers provide a prototypical model for linear sequences containing more turn mimics, which will allow for true synthetic surface confined foldamers.

  DOI：

  10.1021/ja046124j

文献信息

• Design and STM Investigation of Intramolecular Folding in Self-Assembled Monolayers on the Surface
  作者：Norbert Schuurmans、Hiroshi Uji-i、Wael Mamdouh、Frans C. De Schryver、Ben L. Feringa、Jan van Esch、Steven De Feyter

  DOI：10.1021/ja046124j

  日期：2004.11.1

  The rational design of catechol bis-amides rendered molecular structures that fold into beta-turn mimics at the interface of HOPG and 1-octanol as demonstrated by STM. These self-assembled monolayers provide a prototypical model for linear sequences containing more turn mimics, which will allow for true synthetic surface confined foldamers.