Undec-10-enoic acid methyl-((2S,3R,4R,5R)-2,3,4,5,6-pentahydroxy-hexyl)-amide | 87137-92-6

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: Undec-10-enoic acid methyl-((2S,3R,4R,5R)-2,3,4,5,6-pentahydroxy-hexyl)-amide
• CAS: 87137-92-6
• 化学式: C₁₈H₃₅NO₆
• 分子量: 361.479
• InChiKey: QRDKQJLOZMTWDL-BURFUSLBSA-N

物化性质

• 沸点：
  602.7±55.0 °C(Predicted)
• 密度：
  1.150±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  0.19
• 重原子数：
  25.0
• 可旋转键数：
  15.0
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.83
• 拓扑面积：
  121.46
• 氢给体数：
  5.0
• 氢受体数：
  6.0

反应信息

• 作为反应物：
  描述：

  Undec-10-enoic acid methyl-((2S,3R,4R,5R)-2,3,4,5,6-pentahydroxy-hexyl)-amide 在 偶氮二异丁腈 、 氨 作用下， 以 四氢呋喃 为溶剂， 反应 10.0h， 生成
  参考文献：
  名称：

  Arrays for the Combinatorial Exploration of Cell Adhesion

  摘要：

  A new method for the fabrication of arrays of self-assembled monolayers (SAMs) of alkane thiols (ATs) on gold to combinatorially assay surfaces for cell adhesion is reported. A fluorous SAM, which is both cytophobic and solvophobic, was used as the background between the array features. The resulting solvophobic background permits the application of an assembly after conjugation strategy for fabrication. SAMs containing mixtures of ATs and peptide-terminated ATs were generated. Multiple cell types demonstrated differential and specific binding to these surfaces. Additionally, pluripotent human embryonic stem cells proliferated on surfaces generated by this method.

  DOI：

  10.1021/ja0474291
• 作为产物：
  描述：

  10-十一碳烯基氯酸 在 三乙胺 作用下， 以 四氢呋喃 、 N,N-二甲基甲酰胺 为溶剂， 反应 4.0h， 生成 Undec-10-enoic acid methyl-((2S,3R,4R,5R)-2,3,4,5,6-pentahydroxy-hexyl)-amide
  参考文献：
  名称：

  Arrays for the Combinatorial Exploration of Cell Adhesion

  摘要：

  A new method for the fabrication of arrays of self-assembled monolayers (SAMs) of alkane thiols (ATs) on gold to combinatorially assay surfaces for cell adhesion is reported. A fluorous SAM, which is both cytophobic and solvophobic, was used as the background between the array features. The resulting solvophobic background permits the application of an assembly after conjugation strategy for fabrication. SAMs containing mixtures of ATs and peptide-terminated ATs were generated. Multiple cell types demonstrated differential and specific binding to these surfaces. Additionally, pluripotent human embryonic stem cells proliferated on surfaces generated by this method.

  DOI：

  10.1021/ja0474291