trans-[RuIII(NH3)4(H2O)(isonicotinic acid)]3+ | 77761-08-1

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡咯
• 英文名称: trans-[RuIII(NH3)4(H2O)(isonicotinic acid)]3+
• 英文别名: trans-[Ru^III(NH₃)₄(H₂O)(isonicotinic acid)]³⁺；trans-[Ru^III(NH₃)₄(H₂O)(ina)]³⁺；trans-[Ru(NH3)4(4-picoline)(H2O)](3+)；trans-[Ru(NH3)4(4-pic)(H2O)](3+)
• CAS: 77761-08-1
• 化学式: C₆H₁₉N₅O₃Ru
• 分子量: 310.319
• InChiKey: TXGTZBHDQPWFOU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
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• 可旋转键数：
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• 环数：
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• sp3杂化的碳原子比例：
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• 拓扑面积：
  None
• 氢给体数：
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• 氢受体数：
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反应信息

• 作为产物：
  描述：

  trans-[Ru(NO)(NH₃)₄(isonicotinic acid)]³⁺ 、 水 在 sodium 2,2,2-trifluoroacetate 、 三氟乙酸 作用下， 反应 0.5h， 生成 trans-[RuIII(NH3)4(H2O)(isonicotinic acid)]3+ 、 氧化亚氮
  参考文献：
  名称：

  PAMAM dendrimers functionalized with ruthenium nitrosyl as nitric oxide carriers

  摘要：

  The functionalization of three generations of polyamidoamine (PAMAM G0, G2 and G3) dendrimers with the NO-donor trans-[Ru(NO)(NH3)(4)(ina)](BF4)(3) (ina = isonicotinic acid) is reported. PAMAMs were modified through a peptide-type bond between the carboxyl group of the ina ligand and the dendrimer superficial amines. Compounds were characterized by FT-IR, UV-Vis, CV, DPV, H-1 NMR, ICP-OES, and the structure of the complextrans-[Ru(NO)(NH3)(4)(ina)](BF4)(SiF6)center dot H2O was determined by single crystal X-Ray analysis. The experimental data indicated the immobilization of 4, similar to 8 and similar to 27 nitrosyl complexes on the G0, G2 and G3 dendrimer's surface, respectively, which corresponds to similar to 1.0-1.43 mu mol NO per mg of dendrimer. FT-IR, UV-Vis and electrochemical assays suggest that the functionalization of PAMAM did not alter the coordination sphere of the ruthenium nitrosyl complex neither the formal reduction potential of (RuNO+)-N-II/(RuNO0)-N-II couple regarding to the complex not attached to PAMAM. The NO release in these compounds, through light irradiation (lambda = 355 nm) and one-electron reduction (Eu2+), was investigated. (C) 2013 Elsevier B. V. All rights reserved.

  DOI：

  10.1016/j.ica.2013.07.009

文献信息

• Photochemical reactions of trans-[Ru(NH3)4L(NO)]3+ complexes
  作者：Rose M. Carlos、Alessander A. Ferro、Hildo A.S. Silva、Maria G. Gomes、Simone S.S. Borges、Peter C. Ford、Elia Tfouni、Douglas W. Franco

  DOI：10.1016/j.ica.2003.11.023

  日期：2004.3

  L(NO)] 3 - → h v [Ru(NH 3 ) 4 L(H 2 O)] 3 - + NO Quantum yields for [Ru(NH 3 ) 4 L(H 2 O)] 3 formation (Φ R u / I I I ) are sensitive to the natures of L. λ i r r and pH. The lowest quantum yields (λ i r r = 310 nm) were found for L = imidazole (0.03) and i -histidine (0.04). while much higher values were found for L=P(OEt) 3 (0.30). Irradiation at longer wavelengths does not induce photochemical reactivity

  一系列反式-[Ru（NH 3）4 L（NO）] 3 +配合物的光化学行为，其中L =与氮结合的咪唑，L-组氨酸，4-甲基吡啶，吡啶，烟酰胺，吡嗪，4-乙酰基吡啶，或报道了亚磷酸三乙酯。除了配体局部吸收带（<300 nm）以外，这些配合物的电子光谱还被分配为配体场（LF）和金属到配体（dπ→NO）电荷转移（MLCT）跃迁的相对较低强度的谱带所支配。用近紫外光（300-370 nm）辐照这些配合物的水溶液会使NO无效，即反式-[Ru（NH 3）4 L（NO）] 3-→hv [Ru（NH 3）4 L（ H 2 O）] 3-+ NO [Ru（NH 3）4 L（H 2 O）] 3的形成（ΦR u / III）的量子产率对L.λirr和pH的性质敏感。L =咪唑（0。03）和i-组氨酸（0.04）。而L = P（OEt）3（0.30）的值更高。较长波长的辐射不会引起光化学反应性。这些结果是根据这些系统中dπ→NO