lycogarubin A

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吲哚及其衍生物
• 英文名称: lycogarubin A
• 英文别名: Lycogarbin-A；dimethyl 3,4-bis(5-hydroxy-1H-indol-3-yl)-1H-pyrrole-2,5-dicarboxylate
• 化学式: C₂₄H₁₉N₃O₆
• 分子量: 445.431
• InChiKey: GTHIVVRMSDWBAX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.9
• 重原子数：
  33
• 可旋转键数：
  6
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.08
• 拓扑面积：
  140
• 氢给体数：
  5
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  乙酸酐 、 lycogarubin A 在 吡啶 作用下， 生成 3,4-Bis-(5-acetoxy-1H-indol-3-yl)-1H-pyrrole-2,5-dicarboxylic acid dimethyl ester
  参考文献：
  名称：

  Three novel dimethyl pyrroledicarboxylate, lycogarubins AC, from the myxomycetes lycogala epidendrum

  摘要：

  Three novel dimethyl pyrroledicarboxylate, named lycogarubins A-C have been isolated from the Myxomycetes Lycogala epidendrum. Their structures have been established by a combination of two dimension NMR spectroscopy, X-ray crystallographic analysis and chemical degradation. Lycogarubin C showed moderate anti-HSV-I virus activity.

  DOI：

  10.1016/s0040-4039(00)77170-x

文献信息

• Three novel dimethyl pyrroledicarboxylate, lycogarubins AC, from the myxomycetes lycogala epidendrum
  作者：Toshihiro Hashimoto、Yasuda Akiyo、Kyoko Akazawa、Shigeru Takaoka、Motoo Tori、Yoshinori Asakawa

  DOI：10.1016/s0040-4039(00)77170-x

  日期：1994.4

  Three novel dimethyl pyrroledicarboxylate, named lycogarubins A-C have been isolated from the Myxomycetes Lycogala epidendrum. Their structures have been established by a combination of two dimension NMR spectroscopy, X-ray crystallographic analysis and chemical degradation. Lycogarubin C showed moderate anti-HSV-I virus activity.