2-methyl-6-tridecylpiperidine | 35285-26-8

• 分子结构分类: 有机化合物 - 生物碱及其衍生物
• 英文名称: 2-methyl-6-tridecylpiperidine
• 英文别名: NSC-177343
• CAS: 35285-26-8；32778-77-1
• 化学式: C₁₉H₃₉N
• 分子量: 281.525
• InChiKey: AJAXYTHTWGIEHL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.8
• 重原子数：
  20
• 可旋转键数：
  12
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  12
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  2-methyl-6-tridecylpiperidine 、 三氟乙酸酐 在 吡啶 作用下， 以 乙醚 为溶剂， 生成 2,2,2-Trifluoro-1-(2-methyl-6-tridecylpiperidin-1-yl)ethanone
  参考文献：
  名称：

  Absolute Configuration of Solenopsis Piperidines is a Tool to Classify Fire Ants (Formicidae:Myrmicinae)

  摘要：

  Piperidine alkaloids are predominant in ant venom glands of S. invicta and S. saevissima. These ants are broadly sympatric in Southeastern Brazil, and potentially diagnostic compounds could assist in ant identification. We determined the absolute configuration of 2,6-dialkyl-piperidines of S. invicta and S. saevissima workers and used these data to group Southeastern Brazil species. The monitoring of venom samples by chiral gas chromatography coupled to a flame ionization detector (GC-FID) revealed that S. saevissima produces the four stereoisomers of 2-methyl-6-undecylpiperidines, 2-methyl-6-tridecyl-piperidines and 2-methyl-6-tridecenyl-piperidines, while S. invicta venom consisted primarily of a single enantiomer cis and trans from each piperidine alkaloid. Our findings showed that the absolute configuration of piperidine alkaloids of fire ant venom may be a potential chemical tool to distinguish S. invicta and S. saevissima sympatric species in Southeastern Brazil.

  DOI：

  10.21577/0103-5053.20170153
• 作为产物：
  描述：

  6-Methyl-2-tridecyl-1,2,3,6-tetrahydro-pyridine 以96%的产率得到
  参考文献：
  名称：

  SAKANE, SOICHI;MATSUMURA, YASUSHI;YAMAMURA, YOSHIHIRO;ISHIDA, YASUKO;MARU+, J. AMER. CHEM. SOC., 1983, 105, N 3, 672-674

  摘要：

  DOI：

文献信息

• COMPOSITIONS AND METHODS RELATING TO SOLENOPSINS AND THEIR USES IN TREATING NEUROLOGICAL DISORDERS AND ENHANCING PHYSICAL PERFORMANCE
  申请人：Synapsin Pharmaceuticals, Inc.

  公开号：EP2043642A2

  公开（公告）日：2009-04-08
• Compositions And Methods Relating To Solenopsins And Their Uses In Treating Neurological Disorders And Enhancing Physical Performance
  申请人：SYNAPSIN PHARMACEUTICALS, INC.

  公开号：US20140086998A1

  公开（公告）日：2014-03-27

  Provided herein are piperidine alkaloids and uses thereof in neurological disorders and physical enhancement applications.
• US8524741B2
  申请人：——

  公开号：US8524741B2

  公开（公告）日：2013-09-03
• US9259419B2
  申请人：——

  公开号：US9259419B2

  公开（公告）日：2016-02-16
• US9943554B2
  申请人：——

  公开号：US9943554B2

  公开（公告）日：2018-04-17