3-O-Acetylpinobanksin; Pinobanksin 3-O-acetate; Pinobanksin 3-acetate

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 黄酮类化合物
• 英文名称: 3-O-Acetylpinobanksin; Pinobanksin 3-O-acetate; Pinobanksin 3-acetate
• 英文别名: (5,7-dihydroxy-4-oxo-2-phenyl-2,3-dihydrochromen-3-yl) acetate
• 化学式: C₁₇H₁₄O₆
• 分子量: 314.29
• InChiKey: BJYHZSNSMVEQEH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.8
• 重原子数：
  23
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.18
• 拓扑面积：
  93.1
• 氢给体数：
  2
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  3-O-Acetylpinobanksin; Pinobanksin 3-O-acetate; Pinobanksin 3-acetate 、 trimethylsilyl 2,2,2-trifluoro-N-(trimethylsilyl)acetimidate 生成 [4-oxo-2-phenyl-5,7-bis(trimethylsilyloxy)-2,3-dihydrochromen-3-yl] acetate
  参考文献：
  名称：

  GREENAWAY, W.;WHATLEY, F. R., J. CHROMATOGR., 519,(1990) N, C. 145-158

  摘要：

  DOI：

文献信息

• PROPOLIS AND EXTRACTS THEREOF FOR THE TREATMENT OF SKIN CANCERS AND IMPROVEMENT OF SKIN HEALTH
  申请人：Manuka Health New Zealand Limited

  公开号：EP3169321B1

  公开（公告）日：2020-07-15
• PROCESS FOR OBTAINING NON-ALLERGIC PROPOLIS
  申请人：Ricchiuto Giuseppe Maria

  公开号：US20130006011A1

  公开（公告）日：2013-01-03

  The present disclosure relates to a process for pre-treating raw propolis comprising at least one allergenic activity substance, which comprises reacting propolis with a probiotic microorganism containing one or more cinnamoyl-esterase activity enzymes to obtain a semisolid propolis derivative substantially without or impoverished of allergenic substances. The present invention also relates to a method of purifying semisolid propolis derivative to obtain a hydroalcoholic hydrodispersible propolis derivative.
• Therapeutic Compositions and Uses Thereof
  申请人：MANUKA HEALTH NEW ZEALAND LIMITED

  公开号：US20160030364A1

  公开（公告）日：2016-02-04

  This invention provides pharmaceutical compositions comprising compounds including 5-phenylpenta-2,4-dienoic acid, 3-methyl-3-butenyl caffeic acid, 1,1-dimethylallyl caffeic acid, pinobanksin-3-acetate, tectochrysin, pinostrobin chalcone, benzyl ferulate and benzyl isoferulate. Methods of using such compositions, in particular in the treatment or prevention of gastrointestinal cancers, and the resensitisation of gastrointestinal cancers to therapy are also provided.
• Propolis and Extracts Thereof for the Treatment of Skin Cancers and Improvement of Skin Health
  申请人：Manuka Health New Zealand Limited

  公开号：US20170209499A1

  公开（公告）日：2017-07-27

  This invention provides pharmaceutical and cosmeceutical compositions, including anti-skin cancer compositions, N containing propolis and cyclodextrin, and compositions comprising one or more compounds present in propolis, including compositions comprising one or more compounds present as an inclusion complex with cyclodextrin. Methods of using such compounds and compositions, in particular in the treatment or prevention of skin cancers and skin disorders, and in enhancing skin health, are also provided.
• US9072754B2
  申请人：——

  公开号：US9072754B2

  公开（公告）日：2015-07-07