Pectolinarigenin 7-(6''-methylglucuronide)

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 黄酮类化合物
• 英文名称: Pectolinarigenin 7-(6''-methylglucuronide)
• 英文别名: methyl 3,4,5-trihydroxy-6-[5-hydroxy-6-methoxy-2-(4-methoxyphenyl)-4-oxochromen-7-yl]oxyoxane-2-carboxylate
• 化学式: C₂₄H₂₄O₁₂
• 分子量: 504.4
• InChiKey: BWUMQHHQRFRBKZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.7
• 重原子数：
  36
• 可旋转键数：
  7
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  170
• 氢给体数：
  4
• 氢受体数：
  12

文献信息

• SCUTELLARIN AMIDE DERIVATIVES, AND PREPARATION METHODS AND USES THEREOF
  申请人：HEILONGJIANG BAYI AGRICULTURAL UNIVERSITY

  公开号：US20220002332A1

  公开（公告）日：2022-01-06

  The present disclosure discloses scutellarin amide derivatives and preparation methods and uses thereof, which belongs to the field of natural drugs and medicinal chemistry. The scutellarin amide derivatives according to the present disclosure and pharmaceutically acceptable salts thereof have a structure as shown in the following general formula I: scutellarin derivatives, which are prepared by amidation at the glycosylcarboxyl site, can be used in the manufacture of anti-tumor drugs, which have a good effect against tumor cell proliferation.