4-(3-acetyl-4-hydroxy-5-oxo-2-phenyl-2,5-dihydro-1H-pyrrol-1-yl)butanoic acid | 425610-33-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡咯啉
• 英文名称: 4-(3-acetyl-4-hydroxy-5-oxo-2-phenyl-2,5-dihydro-1H-pyrrol-1-yl)butanoic acid
• 英文别名: 4-(3-acetyl-4-hydroxy-5-oxo-2-phenyl-2H-pyrrol-1-yl)butanoic acid
• CAS: 425610-33-9
• 化学式: C₁₆H₁₇NO₅
• 分子量: 303.315
• InChiKey: BXYLWAMRNSCKHT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.2
• 重原子数：
  22
• 可旋转键数：
  6
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.31
• 拓扑面积：
  94.9
• 氢给体数：
  2
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  4-(3-acetyl-4-hydroxy-5-oxo-2-phenyl-2,5-dihydro-1H-pyrrol-1-yl)butanoic acid 、 乙烷,三氯氟- 以 溶剂黄146 为溶剂， 以44%的产率得到(Z)-1-(3-carboxypropyl)-4-[1-(4-methylphenyl)aminoethylidene]-5-phenylpyrrolidine-2,3-dione
  参考文献：
  名称：

  Reaction of 5-aryl-4-acetyl-3-hydroxy-1-(ω-carboxyalkyl)-3-pyrrolin-2-ones with aromatic amines

  摘要：

  Reactions of 5-aryl-4-acetyl-3-hydroxy-1-(omega-carboxyalkyl)-3-pyrrolin-2-ones with aromatic amines led to the formation of 5-aryl-4-(1-arylaminoethylidene)-1-(omega-carboxyalkyl)pyrrolidine-2,3-diones whose structure was confirmed by IR and (1)H NMR spectra and XRD analysis.

  DOI：

  10.1134/s1070428009020181

文献信息

• Reaction of 5-aryl-4-acetyl-3-hydroxy-1-(ω-carboxyalkyl)-3-pyrrolin-2-ones with aromatic amines
  作者：L. F. Gein、V. L. Gein、I. A. Kylosova、Z. G. Aliev

  DOI：10.1134/s1070428009020181

  日期：2010.2

  Reactions of 5-aryl-4-acetyl-3-hydroxy-1-(omega-carboxyalkyl)-3-pyrrolin-2-ones with aromatic amines led to the formation of 5-aryl-4-(1-arylaminoethylidene)-1-(omega-carboxyalkyl)pyrrolidine-2,3-diones whose structure was confirmed by IR and (1)H NMR spectra and XRD analysis.