7,4'-dihydroxy-5-methoxyflavanone | 61823-56-1

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 黄酮类化合物
• 英文名称: 7,4'-dihydroxy-5-methoxyflavanone
• 英文别名: naringenin 5-methyl ether；5-O-methylnaringenin；7-hydroxy-2-(4-hydroxyphenyl)-5-methoxy-2,3-dihydrochromen-4-one
• CAS: 61823-56-1
• 化学式: C₁₆H₁₄O₅
• 分子量: 286.284
• InChiKey: CWZLMWSCLBFCBY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.2
• 重原子数：
  21
• 可旋转键数：
  2
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.19
• 拓扑面积：
  76
• 氢给体数：
  2
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  7,4'-dihydroxy-5-methoxyflavanone 生成 柚皮素
  参考文献：
  名称：

  BAHUGUNA, R. P.;JANGWAN, J. S.;KAIYA, T.;SAKAKIBARA, J., J. NATUR. PROD., 50,(1987) N 2, 232-234

  摘要：

  DOI：
• 作为产物：
  描述：

  2-(4-hydroxyphenyl)-5-methoxy-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2,3-dihydrochromen-4-one 生成 7,4'-dihydroxy-5-methoxyflavanone
  参考文献：
  名称：

  BAHUGUNA, R. P.;JANGWAN, J. S.;KAIYA, T.;SAKAKIBARA, J., J. NATUR. PROD., 50,(1987) N 2, 232-234

  摘要：

  DOI：

文献信息

• Composition Comprising the Extract of Anemarrhena Asphodeloides Bunge or the Compounds Isolated from the Same for Preventing and Treating Lipid Metabolism Disorder
  申请人：Seo Eun Kyoung

  公开号：US20120070515A1

  公开（公告）日：2012-03-22

  The present invention relates to a composition comprising an extract of Anemarrhena asphodeloides Bunge or the compounds isolated from the same, as an active ingredient. In particular, the extract and compounds have the excellent inhibitory effects on adipocyte differentiation, and thus can be used in a pharmaceutical composition and functional food for the prevention and treatment of lipid metabolism disorders.

  本发明涉及一种包含知母提取物或从中分离出的化合物的组合物，作为活性成分。具体来说，该提取物和化合物具有出色的抑制脂肪细胞分化作用，因此可用于制备用于预防和治疗脂质代谢紊乱的药物组合物和功能性食品。
• Flavanone glycosides from Alhagi pseudalhagi
  作者：V.P Singh、Bineeta Yadav、V.B Pandey

  DOI：10.1016/s0031-9422(99)00010-2

  日期：1999.6

  Two new flavanone glycosides, alhagitin and alhagidin, have been isolated from the whole plant of Alhagi pseudalhagi and their structures established respectively as naringenin 5-methyl ether 4'-glucoside and hesperitin 7-galactosyl(1-->2)[rhamnosyl(1-->6)]glucoside by chemical and spectroscopic methods.

  从海参全株中分离得到了两种新的黄烷酮苷，海藻苷和海藻苷，其结构分别为柚皮素5-甲基醚4'-葡萄糖苷和橙皮素7-半乳糖苷(1-->2)[鼠李糖苷(1) -->6)]葡萄糖苷通过化学和光谱方法。
• A chalcone glycoside from Clerodendron phlomidis
  作者：R. Roy、V.B. Pandey

  DOI：10.1016/s0031-9422(00)89613-2

  日期：1994.12

  A new chalcone glycoside, together with pectolinarigenin, 7-hydroxyflavone and 7-hydroxyflavanone 7-O-glucoside have been isolated from the flowers and leaves of Clerodendron phlomidis. The structure of the chalcone glycoside has been established as 4,2',4'-trihydroxy-6'-methoxychalcone 4,4'-D-diglucoside by spectroscopic and degradative methods.

  一种新的查尔酮糖苷，连同果胶甙元、7-羟基黄酮和 7-羟基黄烷酮 7-O-葡萄糖苷已从 Clerodendron phlomidis 的花和叶中分离出来。查尔酮糖苷的结构已通过光谱和降解方法确定为 4,2',4'-三羟基-6'-甲氧基查尔酮 4,4'-D-二葡萄糖苷。
• Anam, Edet M., Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 1999, vol. 38, # 11, p. 1307 - 1310
  作者：Anam, Edet M.

  DOI：——

  日期：——
• Zemplen et al., Chemische Berichte, 1944, vol. 77/79, p. 446,449
  作者：Zemplen et al.

  DOI：——

  日期：——