2,5-Dipropylthiazole | 41981-73-1

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: 2,5-Dipropylthiazole
• 英文别名: 2,5-dipropyl-1,3-thiazole
• CAS: 41981-73-1
• 化学式: C₉H₁₅NS
• mdl: MFCD18451318
• 分子量: 169.29
• InChiKey: CXXDPLSFABWHEQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.3
• 重原子数：
  11
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.666
• 拓扑面积：
  41.1
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• PIF BINDING AS A MARKER FOR IMMUNE DYSREGULATION
  申请人：BioIncept, LLC

  公开号：US20170336406A1

  公开（公告）日：2017-11-23

  Embodiments are directed to methods of examining preimplantation factor (PIF) binding to a subject's circulating immune cells as a marker for immune dysregulation. Some embodiments are directed to methods of detecting a level of immune dysregulation sufficient to cause recurrent pregnancy loss (RPL), methods of detecting a level of immune dysfunction sufficient to cause endometriosis, and methods of detecting a level of immune dysfunction comprising administering an effective amount of PIF or an analog thereof, and examining its binding to circulating immune cells. Within those methods, an about twenty percent change in PIF binding to a subject's circulating immune cells indicates a level of immune dysfunction.