7-[4-(5,7-Dihydroxy-4-oxochromen-2-yl)phenoxy]-5,8-dihydroxy-2-(4-hydroxyphenyl)chromen-4-one

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 黄酮类化合物
• 英文名称: 7-[4-(5,7-Dihydroxy-4-oxochromen-2-yl)phenoxy]-5,8-dihydroxy-2-(4-hydroxyphenyl)chromen-4-one
• 化学式: C₃₀H₁₈O₁₀
• 分子量: 538.5
• InChiKey: DFAXUEHGJFANJA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.3
• 重原子数：
  40
• 可旋转键数：
  4
• 环数：
  6.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  163
• 氢给体数：
  5
• 氢受体数：
  10

文献信息

• METHOD OF IMPROVING STABILITY OF SWEET ENHANCER AND COMPOSITION CONTAINING STABILIZED SWEET ENHANCER
  申请人：TACHDJIAN Catherine

  公开号：US20120041078A1

  公开（公告）日：2012-02-16

  The present invention includes methods of stabilizing one or more sweet enhancers when they are exposed to a light source as well as liquid compositions containing one or more sweet enhancers and one or more photostabilizers.

  本发明包括在甜味增强剂暴露于光源时稳定一个或多个甜味增强剂的方法，以及包含一个或多个甜味增强剂和一个或多个光稳定剂的液体组合物。
• GLUCOSYRINGIC ACID ANALOGS AS SWEETNESS PROFILE MODIFIERS
  申请人：PepsiCo, Inc.

  公开号：US20180020708A1

  公开（公告）日：2018-01-25

  The present disclosure provides novel sweetener compositions comprising a compound having a structure according to Formula I: wherein R 1 , R 2 , R 3 , and R 4 are described herein. Also provided are methods of modulating sweetness profile of a product by adding a compound of Formula I to the product, such as a beverage product or a food product. For example, the compound described herein can be added to increase the overall sweetness of a nutritive sweetener sweetened beverages; decrease the sweetness time-of-onset for high potency sweeteners such as rebaudioside A; decreasing bitter, metallic and licorice off-notes of high potency sweeteners; and improve the sweet quality of sweetened products.

  本公开提供了包含具有如下式I的结构的化合物的新型甜味剂组合物： 其中R1、R2、R3和R4如本文所述。还提供了通过向产品添加式I的化合物来调节产品的甜味特性的方法，例如饮料产品或食品产品。例如，本文描述的化合物可添加以增加富含甜味剂的饮料的整体甜度；减少高效甜味剂（如甜菊糖A）的甜味起始时间；减少高效甜味剂的苦味、金属味和甘草味等异味；并改善甜味产品的甜味质量。
• Rebaudioside Analogs
  申请人：PepsiCo, Inc.

  公开号：US20180016291A1

  公开（公告）日：2018-01-18

  The present disclosure provides novel compounds that are steviol derivatives. The compounds generally can be characterized by a structure according to Formula I: wherein A 1 , L 1 , and G 1 are described herein. Also provided are sweetener compositions comprising the compound described herein either as a sweetener or a sweetener enhancer. Additionally, the compound or the sweetener composition can be included in a product such as a beverage product or a food product, which can reduce the amount of sweetener in the product required to achieve the same sweetness level in an otherwise identical product not including the compound or the sweetener composition.

  本公开提供了一些新颖的化合物，这些化合物是史蒂维醇衍生物。这些化合物通常可通过以下式I所示的结构来表征：其中A1、L1和G1如本文所述。还提供了包含所述化合物的甜味剂组合物，可以作为甜味剂或增甜剂。此外，该化合物或甜味剂组合物可以包含在产品中，例如饮料产品或食品产品中，可以减少产品中所需的甜味剂量，以达到在另一种不包含该化合物或甜味剂组合物的相同产品中所需的甜度水平。
• Amentoflavone as an antiviral agent
  申请人：Advanced Life Sciences Inc.

  公开号：EP1245230A2

  公开（公告）日：2002-10-02

  Substantially purified antiviral biflavanoids robustaflavone, hinokiflavone, amentoflavone, agathisflavone, volkensiflavone, morelloflavone, rhusflavanone, succedaneaflavanone, GB-1a and GB-2a are provided. Antiviral fiflavanoid derivatives and salt forms thereof, e.g. robustaflavone tetrasulfate potassium salt, and methods for preparing the same are also disclosed. Pharmaceutical compositions which include the antiviral biflavanoids, derivatives or salts thereof are also provided. Also disclosed is an improved method for obtaining substantially pure robustaflavone from plant material. The biflavanoid compounds, derivatives or salts thereof of the invention may be used in a method for treating and/or preventing viral infections caused by viral agents such as influenza, e.g. influenza A and B; hepatitis, e.g. hepatitis B; human immunodeficiency virus, e.g. HIV-1; Herpes viruses (HSV-1 and HSV-2); Varicella Zoster virus (VZV); and measles.

  本研究提供了实质上纯化的抗病毒双黄酮类化合物--强力黄酮、桧黄酮、芒果黄酮、芒果黄酮、伏肯黄酮、麦卢黄酮、胡黄酮、琥珀黄酮、GB-1a 和 GB-2a。此外，还公开了抗病毒的五黄烷衍生物及其盐形式，例如强力黄酮四硫酸钾盐，以及制备方法。还提供了包括抗病毒双黄烷、衍生物或其盐的药物组合物。此外，还公开了一种从植物材料中获得高纯度强力黄酮的改进方法。本发明的双黄烷化合物、衍生物或其盐类可用于治疗和/或预防由病毒病原体引起的病毒感染，如流感，如甲型和乙型流感；肝炎，如乙型肝炎；人类免疫缺陷病毒，如 HIV-1；疱疹病毒（HSV-1 和 HSV-2）；水痘带状疱疹病毒（VZV）；以及麻疹。
• Beverage composition and method of preventing degradation of vitamins in beverages
  申请人：PepsiCo, Inc.

  公开号：EP1782701A1

  公开（公告）日：2007-05-09

  A vitamin fortified composition comprising vitamin stabilizers which are C6-C3 phenylpropenoic carbonyl compounds to prevent the degradation of the vitamins is provided. In addition, a method of preventing the degradation of vitamins in a vitamin fortified composition is provided.

  本发明提供了一种维生素强化组合物，其中包含维生素稳定剂（C6-C3 苯丙烯酰羰基化合物），以防止维生素降解。此外，还提供了一种防止维生素强化组合物中维生素降解的方法。