3,5,7-trihydroxyflavan

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 黄酮类化合物
• 英文名称: 3,5,7-trihydroxyflavan
• 英文别名: pinobanksine；2-phenylchromane-3,5,7-triol；2-phenyl-3,4-dihydro-2H-chromene-3,5,7-triol
• 化学式: C₁₅H₁₄O₄
• 分子量: 258.274
• InChiKey: DGEMVQDNZRCAGP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.1
• 重原子数：
  19
• 可旋转键数：
  1
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  69.9
• 氢给体数：
  3
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  2-hydroxy-ω,4,6-tribenzyloxyacetophenone 在 4-二甲氨基吡啶 、 四丁基溴化铵 、 potassium carbonate 、 三乙胺 作用下， 生成 3,5,7-trihydroxyflavan
  参考文献：
  名称：

  POLYPHENOL COMPOUNDS

  摘要：

  The present application discloses derivatives of polyphenols, pharmaceutically acceptable salts, stereoisomers or tautomers thereof, and processes for preparation thereof. The compounds and compositions described herein can be used in therapy.

  公开号：

  US20240254135A1

文献信息

• NOVEL ANALOGUES OF EPICATECHIN AND RELATED POLYPHENOLS
  申请人：SPHAERA PHARMA PVT. LTD.

  公开号：US20160039781A1

  公开（公告）日：2016-02-11

  The present invention provides novel analogues of epicatechin and related polyphenols, their variously functionalized derivatives, process for preparation of the same, composition comprising these compounds and their method of use.

  本发明提供了表儿茶素及相关多酚的新颖类似物，它们的各种官能化衍生物，以及它们的制备方法、包含这些化合物的组合物和它们的使用方法。
• Microbial polycultures and methods of use thereof
  申请人：RENSSELAER POLYTECHNIC INSTITUTE

  公开号：US10954543B2

  公开（公告）日：2021-03-23

  Disclosed herein are novel microbial polycultures of two or more cell strains, capable of producing flavanones, flavonoids, and anthocyanidin-3-O-glucosides, and methods of use thereof. Also disclosed is a microbial cell capable of producing phenylpropanoic acids, and methods of use thereof.

  本文公开了由两种或两种以上细胞株组成的新型微生物多培养物，它们能够生产黄烷酮、黄酮类化合物和花青素-3-O-葡萄糖苷，以及使用方法。还公开了一种能够生产苯丙酸的微生物细胞及其使用方法。
• ORAL CARE
  申请人：University of Pretoria

  公开号：EP2888012A2

  公开（公告）日：2015-07-01
• LIVER FUNCTION AND TREATMENT OF LIVER DISEASE
  申请人：Chang Shau-Feng

  公开号：US20110158933A1

  公开（公告）日：2011-06-30

  A pharmaceutical preparation containing polymeric compounds as shown in the specification. This preparation can be used to improve liver function and treat liver disease, and promoting liver tissue regeneration.
• MICROBIAL POLYCULTURES AND METHODS OF USE THEREOF
  申请人：RENSSELAER POLYTECHNIC INSTITUTE

  公开号：US20170121748A1

  公开（公告）日：2017-05-04

  Disclosed herein are novel microbial polycultures of two or more cell strains, capable of producing flavanones, flavonoids, and anthocyanidin-3-O-glucosides, and methods of use thereof. Also disclosed is a microbial cell capable of producing phenylpropanoic acids, and methods of use thereof.