2-[15-butan-2-yl-6-[(4-methoxyphenyl)methyl]-3,10,16,19,22,28-hexamethyl-2,5,8,11,14,17,20,23,26,29-decaoxo-9,18,24,27-tetra(propan-2-yl)-4-oxa-1,7,10,13,16,19,22,25,28-nonazabicyclo[28.4.0]tetratriacontan-21-yl]acetic acid

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 肽模拟物
• 英文名称: 2-[15-butan-2-yl-6-[(4-methoxyphenyl)methyl]-3,10,16,19,22,28-hexamethyl-2,5,8,11,14,17,20,23,26,29-decaoxo-9,18,24,27-tetra(propan-2-yl)-4-oxa-1,7,10,13,16,19,22,25,28-nonazabicyclo[28.4.0]tetratriacontan-21-yl]acetic acid
• 化学式: C₅₆H₈₉N₉O₁₄
• 分子量: 1112.4
• InChiKey: DIYFOMLSLDLOMV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.1
• 重原子数：
  79
• 可旋转键数：
  11
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.7
• 拓扑面积：
  282
• 氢给体数：
  4
• 氢受体数：
  14

文献信息

• Gene involved in synthesis of cyclic peptide compound, method for producing cyclic peptide compound using the same, and transformant comprising the same
  申请人：NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY

  公开号：US11230726B2

  公开（公告）日：2022-01-25

  This invention is intended to identify a gene cluster involved in biosynthesis of a cyclic peptide compound produced by a filamentous fungus of the Curvularia species and to establish a system for synthesizing such cyclic peptide compound. The gene is composed of a first module to a tenth module and encodes a protein having activity of synthesizing a nonribosomal peptide constituting a basic peptide backbone of a cyclic peptide compound produced by a filamentous fungus of the Curvularia species.

  本发明旨在鉴定一个参与由 Curvularia 丝状真菌产生的环肽化合物生物合成的基因簇，并建立一个合成这种环肽化合物的系统。该基因由第一模块至第十模块组成，编码一种蛋白质，该蛋白质具有合成非核糖体肽的活性，这种非核糖体肽构成卷曲孢属丝状真菌产生的环肽化合物的碱性肽骨。
• GENE INVOLVED IN SYNTHESIS OF CYCLIC PEPTIDE COMPOUND, METHOD FOR PRODUCING CYCLIC PEPTIDE COMPOUND USING THE SAME, AND TRANSFORMANT COMPRISING THE SAME
  申请人：NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY

  公开号：US20190316164A1

  公开（公告）日：2019-10-17

  This invention is intended to identify a gene cluster involved in biosynthesis of a cyclic peptide compound produced by a filamentous fungus of the Curvularia species and to establish a system for synthesizing such cyclic peptide compound. The gene is composed of a first module to a tenth module and encodes a protein having activity of synthesizing a nonribosomal peptide constituting a basic peptide backbone of a cyclic peptide compound produced by a filamentous fungus of the Curvularia species.