1,2-bis-((S,S)-2,4-dicyclohexylphosphetano)ethane | 256442-54-3

• 分子结构分类: 有机化合物 - 有机磷化合物 - 有机膦及其衍生物
• 英文名称: 1,2-bis-((S,S)-2,4-dicyclohexylphosphetano)ethane
• 英文别名: (2S,4S)-2,4-dicyclohexyl-1-[2-[(2S,4S)-2,4-dicyclohexylphosphetan-1-yl]ethyl]phosphetane
• CAS: 256442-54-3
• 化学式: C₃₂H₅₆P₂
• 分子量: 502.744
• InChiKey: PIQCTVRKYSDHCR-YDPTYEFTSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  9.7
• 重原子数：
  34
• 可旋转键数：
  7
• 环数：
  6.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为反应物：
  描述：

  tris(triphenylphosphine)ruthenium(II) chloride 、 1,2-bis-((S,S)-2,4-dicyclohexylphosphetano)ethane 以 二氯甲烷 为溶剂， 生成 trans-Cl2Ru(1,2-bis((S,S)-2,4-dicyclohexylphosphetano)ethane)2
  参考文献：
  名称：

  Chiral 1,2-bis(phosphetano)ethanes

  摘要：

  Optically pure 1,2-bis(phosphetano)ethanes 3 (BPE-4) have been prepared from 1,2-bis(phosphino)ethane and the cyclic sulfates of symmetrical anti-1,3-diols. Diphosphine 3c (R = cyclohexyl) is an easily accessible, air-stable chiral ligand. Its suitability to the ruthenium-catalysed hydrogenation of functionalised ketones has been examined by using several catalyst precursors. Significant enantiomeric excesses were obtained. A ruthenium complex containing two coordinated diphosphines 3e was characterised by X-ray diffraction studies. (C) 2001 Elsevier Science B.V. All rights reserved.

  DOI：

  10.1016/s0022-328x(00)00910-4
• 作为产物：
  描述：

  (R,R)-1,3-Dicyclohexyl-1,3-propanediol cyclic sulfate 在 三乙烯二胺 作用下， 以 苯 为溶剂， 反应 6.0h， 生成 1,2-bis-((S,S)-2,4-dicyclohexylphosphetano)ethane
  参考文献：
  名称：

  Chiral 1,2-bis(phosphetano)ethanes

  摘要：

  Optically pure 1,2-bis(phosphetano)ethanes 3 (BPE-4) have been prepared from 1,2-bis(phosphino)ethane and the cyclic sulfates of symmetrical anti-1,3-diols. Diphosphine 3c (R = cyclohexyl) is an easily accessible, air-stable chiral ligand. Its suitability to the ruthenium-catalysed hydrogenation of functionalised ketones has been examined by using several catalyst precursors. Significant enantiomeric excesses were obtained. A ruthenium complex containing two coordinated diphosphines 3e was characterised by X-ray diffraction studies. (C) 2001 Elsevier Science B.V. All rights reserved.

  DOI：

  10.1016/s0022-328x(00)00910-4

文献信息

• Chiral 1,2-bis(phosphetano)ethanes
  作者：Angela Marinetti、Sébastien Jus、Jean-Pierre Genêt、Louis Ricard

  DOI：10.1016/s0022-328x(00)00910-4

  日期：2001.4

  Optically pure 1,2-bis(phosphetano)ethanes 3 (BPE-4) have been prepared from 1,2-bis(phosphino)ethane and the cyclic sulfates of symmetrical anti-1,3-diols. Diphosphine 3c (R = cyclohexyl) is an easily accessible, air-stable chiral ligand. Its suitability to the ruthenium-catalysed hydrogenation of functionalised ketones has been examined by using several catalyst precursors. Significant enantiomeric excesses were obtained. A ruthenium complex containing two coordinated diphosphines 3e was characterised by X-ray diffraction studies. (C) 2001 Elsevier Science B.V. All rights reserved.