1-[2,4-Dihydroxy-6-(3,4,5-trihydroxy-6-methyloxan-2-yl)oxyphenyl]-3-(4-hydroxyphenyl)propan-1-one

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 黄酮类化合物
• 英文名称: 1-[2,4-Dihydroxy-6-(3,4,5-trihydroxy-6-methyloxan-2-yl)oxyphenyl]-3-(4-hydroxyphenyl)propan-1-one
• 化学式: C₂₁H₂₄O₉
• 分子量: 420.4
• InChiKey: GLLUYNRFPAMGQR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.3
• 重原子数：
  30
• 可旋转键数：
  6
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.38
• 拓扑面积：
  157
• 氢给体数：
  6
• 氢受体数：
  9

文献信息

• [EN] ACYLATED DERIVATIVES OF PHLORIDZIN AND ISOQUERCETRIN AS ANTICANCER THERAPEUTICS AND METHODS OF USE THEREOF<br/>[FR] DÉRIVÉS ACYLÉS DE PHLORIDZINE ET D'ISOQUERCÉTRINE EN TANT QU'AGENTS THÉRAPEUTIQUES ANTICANCÉREUX ET LEURS PROCÉDÉS D'UTILISATION
  申请人：UNIV DALHOUSIE

  公开号：WO2015019193A2

  公开（公告）日：2015-02-12

  The present specification is directed to an acylated flavonoid derivative derived from natural or synthetic flavonoids and fatty acids. The acylated flavonoid derivatives can be part of a pharmaceutical composition. Method of decreasing proliferation and viability of cancer cells in a subject include administering the disclosed pharmaceutical composition.