3,5,7-Trihydroxy-2-(4-hydroxy-3-methylphenyl)chromen-4-one

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 黄酮类化合物
• 英文名称: 3,5,7-Trihydroxy-2-(4-hydroxy-3-methylphenyl)chromen-4-one
• 化学式: C₁₆H₁₂O₆
• 分子量: 300.26
• InChiKey: GQODBWLKUWYOFX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.3
• 重原子数：
  22
• 可旋转键数：
  1
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.06
• 拓扑面积：
  107
• 氢给体数：
  4
• 氢受体数：
  6

文献信息

• Verfahren zur Herstellung von Wirkstoffkonzentraten
  申请人：Cognis IP Management GmbH

  公开号：EP2060251B1

  公开（公告）日：2011-03-23
• APPROACH FOR SYNTHESIS OF CATECHINS
  申请人：Epirium Bio Inc.

  公开号：EP2948437B1

  公开（公告）日：2021-11-03
• Use of halogenated hydroxydiphenyl ether compounds for the treatment of the skin
  申请人：Baschong Werner

  公开号：US20080279794A1

  公开（公告）日：2008-11-13

  The use of (a) hydroxydiphenyl ether compounds of formula wherein R 1 , R 2 and R 3 are each independently of the others hydrogen; hydroxy; C 1 -C 20 alkyl; hydroxy-substituted C 1 -C 20 alkyl; C 5 -C 7 cycloalkyl; C 1 -C 20 alkoxy; C 1 -C 6 alkylcarbonyl; phenyl; or phenyl-C 1 -C 3 alkyl; R 4 is hydrogen, C 1 -C 20 alkyl; hydroxy-substituted C 1 -C 20 alkyl; C 5 -C 7 cycloalkyl; hydroxy; formyl; acetonyl; allyl; carboxy; carboxy-C 1 -C 3 alkyl; carboxyallyl; C 2 -C 20 alkenyl; C 1 -C 6 alkylcarbonyl; C 1 -C 3 alkylcarbonyl-C 1 -C 3 alkyl; phenyl; or phenyl-C 1 -C 3 alkyl; and R 5 is hydrogen; C 1 -C 20 alkoxy; or C 1 -C 6 alkylcarbonyl; as melanogenesis inhibitors and for lightening the skin.
• PYRONE ANALOG COMPOSITIONS AND METHODS
  申请人：Robbins Wendye

  公开号：US20110190514A1

  公开（公告）日：2011-08-04

  Novel pyrone analogs are described which can enhance the effectiveness of a therapeutic agent when administered and/or reduce side effects caused by the administration of a therapeutic agent.
• Compositions Comprising A Polypeptide Having Cellulolytic Enhancing Activity And A Bicyclic Compound And Uses Thereof
  申请人：Quinlan Jason

  公开号：US20130217077A1

  公开（公告）日：2013-08-22

  The present invention relates to compositions comprising: a polypeptide having cellulolytic enhancing activity and a bicyclic compound. The present invention also relates to methods of using the compositions.