2,5-dihydroxy-7-methoxy-8-methylflavanone | 186906-53-6

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 黄酮类化合物
• 英文名称: 2,5-dihydroxy-7-methoxy-8-methylflavanone
• 英文别名: 2,5-dihydroxy-7-methoxy-8-methyl-2-phenyl-3H-chromen-4-one
• CAS: 186906-53-6
• 化学式: C₁₇H₁₆O₅
• 分子量: 300.311
• InChiKey: GTJNJTZVMPKMRD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.7
• 重原子数：
  22
• 可旋转键数：
  2
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.24
• 拓扑面积：
  76
• 氢给体数：
  2
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  2,5-dihydroxy-6-methyl-7-methoxyflavanone 以 氘代氯仿 为溶剂， 反应 0.08h， 以50%的产率得到2,5-dihydroxy-7-methoxy-8-methylflavanone
  参考文献：
  名称：

  2-Hydroxyflavanones from Leptospermum polygalifolium subsp. polygalifoliumEquilibrating sets of hemiacetal isomers

  摘要：

  2,5-Dihydroxy-6-methyl-7-methoxyflavanone and its isomer 2,5-dihydroxy-8-methyl-7-methoxyflavanone have been identified as the principal components in the ethanol extract of L. polygal folium subsp. polygalifolium. The former compound has been separated from the latter for the first time by crystallisation. Other flavonoids identified include an equilibrating mixture of novel 2,3,5-trihydroxyflavanones; the first discovery of this type of compound from a natural source. This study has also confirmed the presence of the triketones, flavesone and leptospermone, along with the closely related isoleptospermone as anti-microbial components. (C) 2003 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.phytochem.2003.09.006