1,4-bis(4'-methoxyphenyl)-1,4-dimethoxybutane | 80634-51-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 1,4-bis(4'-methoxyphenyl)-1,4-dimethoxybutane
• 英文别名: 1-[1,4-Dimethoxy-4-(4-methoxyphenyl)butyl]-4-methoxybenzene
• CAS: 80634-51-1
• 化学式: C₂₀H₂₆O₄
• 分子量: 330.424
• InChiKey: PFEBLHCKDFARND-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.6
• 重原子数：
  24
• 可旋转键数：
  9
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.4
• 拓扑面积：
  36.9
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  甲醇 、 1,2-di-p-methoxyphenylcyclobutane 在 ammonium cerium(IV) nitrate 作用下， 反应 1.0h， 以62%的产率得到1,4-bis(4'-methoxyphenyl)-1,4-dimethoxybutane
  参考文献：
  名称：

  铈（IV）硝酸铵介导的环丁烷和氧杂环丁烷的氧化重排

  摘要：

  描述了一种简单的CAN介导的烷氧基芳基环丁烷和氧杂环丁烷的氧化重排。

  DOI：

  10.1016/s0040-4039(03)00978-x

文献信息

• ELECTROCHEMICAL OXIDATION OF AROMATIC OLEFINS. DEPENDENCE OF THE REACTION COURSE ON THE STRUCTURE OF THE OLEFINS AND ON THE NATURE OF THE ANODES
  作者：Masanobu Kojima、Hirochika Sakuragi、Katsumi Tokumaru

  DOI：10.1246/cl.1981.1707

  日期：1981.12.5

  Anodic oxidation of a series of substituted styrenes was investigated in methanol with a platinum and a graphite electrode. Use of the platinum anode gave mainly dimethoxylated monomers accompanied with one or more of three types of dimethoxylated dimers (αα-, αβ-, and ββ-dimers) depending on the substituents. Use of the graphite anode, however, afforded the ββ-dimers as the main product together with

  用铂和石墨电极在甲醇中研究了一系列取代苯乙烯的阳极氧化。根据取代基的不同，铂阳极的使用主要产生二甲氧基化单体，并伴有三种类型的二甲氧基化二聚体（αα-、αβ-和ββ-二聚体）中的一种或多种。然而，石墨阳极的使用提供了作为主要产物的 ββ-二聚体以及二甲氧基化单体。
• Photochemical Electron-transfer Reaction between Aromatic Olefins and Metal Ions. Dependence of the Reaction Course on the Structure of the Olefins
  作者：Masanobu Kojima、Hirochika Sakuragi、Katsumi Tokumaru

  DOI：10.1246/bcsj.58.521

  日期：1985.2

  To investigate the photochemical electron transfer from aromatic olefins to copper(II) or iron(III) ions, a series of substituted styrenes (1) was irradiated in the presence of copper(II) or iron(III) salts in methanol, which gave dimethoxylated monomers (2) and one or more of three types of dimethoxylated dimers [α,α- (3), α,β- (4), and β,β,-dimers (5)]. The formation of these products are reasonably

  为了研究从芳族烯烃到铜 (II) 或铁 (III) 离子的光化学电子转移，在甲醇中存在铜 (II) 或铁 (III) 盐的情况下照射一系列取代的苯乙烯 (1)，得到二甲氧基化单体(2)和三种二甲氧基化二聚体[α,α-(3)、α,β-(4)和β,β,-二聚体(5)]中的一种或多种。这些产物的形成合理地归因于通过电子从受激烯烃转移到金属离子而产生的烯烃的阳离子自由基的参与。发现底物上的取代基控制反应产物。
• Electricity-driven 1,4-alkoxydimerization of alkenes <i>via</i> radical–polar crossover
  作者：Yu-Fang Tan、Dan Yang、Yu-Hao Yang、Jin-Feng Lv、Lan-Xi Zong、Zhi Guan、Yan-Hong He

  DOI：10.1039/d3gc02701e

  日期：——

  process for the (homo)cross-1,4-alkoxydimerization of alkenes is described. A variety of abundant and readily available (hetero)aryl alkenes and (halo)aliphatic alcohols can be used in the reaction to produce 1,4-dialkoxybutane derivatives in moderate to excellent yields. Alcohols serve as solvents and nucleophiles, participating in the reaction under mild and environmentally friendly conditions without

  在本文中，描述了烯烃的（均）交叉 1,4-烷氧基二聚化的电驱动自由基-极性交叉过程。各种丰富且容易获得的（杂）芳基烯烃和（卤代）脂肪醇可用于该反应，以中等至优异的产率生产 1,4-二烷氧基丁烷衍生物。醇作为溶剂和亲核试剂，在温和且环保的条件下参与反应，不需要金属或氧化剂。该反应表现出广泛的官能团耐受性和高产物多样性。该反应的唯一副产物是在阴极释放的氢气，使得该方法清洁且高度原子经济。对空气的不敏感性使得该合成策略能够高效且方便地构建各种1,4-二烷氧基丁烷衍生物。克级电化学实验进一步证明了该方法的合成效用。
• Novel Cerium(IV) ammonium nitrate induced dimerization of methoxystyrenes
  作者：Vijay Nair、Jessy Mathew、Puthuparampil P. Kanakamma、Sreeletha B. Panicker、V. Sheeba、S. Zeena、Guenter K. Eigendorf

  DOI：10.1016/s0040-4039(97)00279-7

  日期：1997.3

  Methoxystyrenes undergo facile dimerization when heated with Cerium (IV) ammonium nitrate in methanol; cyclized products are obtained in acetonitrile. (C) 1997 Elsevier Science Ltd.
• Cerium(IV) Ammonium Nitrate Induced Dimerization of Methoxystyrenes
  作者：Vijay Nair、V. Sheeba、Sreeletha B. Panicker、Tesmol G. George、Roshini Rajan、Lakshmi Balagopal、M. Vairamani、S. Prabhakar

  DOI：10.1016/s0040-4020(00)00054-5

  日期：2000.4

  4-Methoxystyrene 1 underwent dimerization to 1,4-diphenylbutane derivatives 5 and 6 in presence of CAN in methanol. But in ethanol the same reaction afforded a tetralone derivative along with 5 and 6. 3,4-Dimethoxystyrene 10 underwent dimerization in presence of CAN in methanol to afford acyclic as well as cyclic products. 3,4,5-Trimethoxystyrene 12 in presence of CAN in methanol afforded only the cyclized dimers, the tetralone 21 and the tetralin derivative 22. (C) 2000 Elsevier Science Ltd. All rights reserved.