3,5-diacetyl-1,7-diphenyl-1,7-dihydro-pyrazolo[4,3-f]indazole

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: 3,5-diacetyl-1,7-diphenyl-1,7-dihydro-pyrazolo[4,3-f]indazole
• 英文别名: 3,5-Diacetyl-1,7-diphenyl-1,7-dihydro-pyrazolo[4,3-f]indazol；1-(3-Acetyl-1,7-diphenylpyrazolo[4,3-f]indazol-5-yl)ethanone
• 化学式: C₂₄H₁₈N₄O₂
• 分子量: 394.433
• InChiKey: IYHXVLYZGFJGMA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.6
• 重原子数：
  30
• 可旋转键数：
  4
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.08
• 拓扑面积：
  69.8
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  1,5-diacetonyl-2,4-dinitro-benzene 在 吡啶 、 sodium hydroxide 、 乙醇 、 sodium acetate 作用下， 生成 3,5-diacetyl-1,7-diphenyl-1,7-dihydro-pyrazolo[4,3-f]indazole
  参考文献：
  名称：

  E MERGENCY M EDICAL P LANNING FOR THE 2000 R EPUBLICAN N ATIONAL C ONVENTION

  摘要：

  Planning for emergency medical services (EMS) coverage for the 2000 Republican National Convention in Philadelphia was a complex process that involved the cooperation of municipal, state, and federal agencies as well as local hospitals. The medical needs of the delegates, members of the media, and support personnel at the convention venue had to be met. Contingency plans for the possibility of large, organized political protests and associated injuries had to be developed. Steps had to be taken to ensure the safety of emergency personnel who may have to respond to such incidents. Because of the heightened threat of terrorist attacks on civilian populations in recent years, specialized training and material to respond to such incidents were required. The important role that local hospitals may play in providing care to victims of a large, multicasualty incident, especially one involving weapons of mass destruction, was recognized. Therefore, steps were taken to increase the awareness of hospital staff to patient decontamination and isolation techniques as well as specific therapies for the chemical, biological, and radioactive agents that terrorists might use. Finally, despite the focus placed on the convention, the day-to-day emergency medical needs of the citizens of Philadelphia had to be met. Through careful planning, flexibility, and cooperation, it was possible to successfully address all of these issues.

  DOI：

  10.1080/10903120190939490

文献信息

• E MERGENCY M EDICAL P LANNING FOR THE 2000 R EPUBLICAN N ATIONAL C ONVENTION
  作者：C. Crawford Mechem、Steven Hare、Robert Hvisdas、David M. Berg、Ralph Halper、Leonard A. Cola

  DOI：10.1080/10903120190939490

  日期：2001.1

  Planning for emergency medical services (EMS) coverage for the 2000 Republican National Convention in Philadelphia was a complex process that involved the cooperation of municipal, state, and federal agencies as well as local hospitals. The medical needs of the delegates, members of the media, and support personnel at the convention venue had to be met. Contingency plans for the possibility of large, organized political protests and associated injuries had to be developed. Steps had to be taken to ensure the safety of emergency personnel who may have to respond to such incidents. Because of the heightened threat of terrorist attacks on civilian populations in recent years, specialized training and material to respond to such incidents were required. The important role that local hospitals may play in providing care to victims of a large, multicasualty incident, especially one involving weapons of mass destruction, was recognized. Therefore, steps were taken to increase the awareness of hospital staff to patient decontamination and isolation techniques as well as specific therapies for the chemical, biological, and radioactive agents that terrorists might use. Finally, despite the focus placed on the convention, the day-to-day emergency medical needs of the citizens of Philadelphia had to be met. Through careful planning, flexibility, and cooperation, it was possible to successfully address all of these issues.