3,4,5-Trihydroxy-6-[5-hydroxy-2-(4-hydroxyphenyl)-4-oxochromen-7-yl]oxyoxane-2-carboxylic acid

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 黄酮类化合物
• 英文名称: 3,4,5-Trihydroxy-6-[5-hydroxy-2-(4-hydroxyphenyl)-4-oxochromen-7-yl]oxyoxane-2-carboxylic acid
• 化学式: C₂₁H₁₈O₁₁
• 分子量: 446.4
• InChiKey: JBFOLLJCGUCDQP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.2
• 重原子数：
  32
• 可旋转键数：
  4
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.24
• 拓扑面积：
  183
• 氢给体数：
  6
• 氢受体数：
  11

文献信息

• [EN] THE USE OF AN EXTRACT OF HELICHRYSUM, FOR THE TREATMENT OF HIV/AIDS<br/>[FR] UTILISATION D'UN EXTRAIT D'HÉLICHRYSUM, POUR LE TRAITEMENT DU VIH/SIDA
  申请人：CSIR

  公开号：WO2011001208A1

  公开（公告）日：2011-01-06

  The invention provides the use of an extract of a plant of the genus Helichrysum, the extract including at least three compounds selected from 3-caffeoylquinic acid (3- chlorogenic acid), 5-caffeoylquinic acid (5-chlorogenic acid), 1,3-di-O-caffeoyl quinic acid, 1,5-di-O-caffeoylquinic acid, 1-methoxy-oxalyl-3,5-di-O-caffeoylquinic acid and kaempferol-3-glucuronic acid in the preparation of a medicament for one or both of the management and treatment of HIV/AIDS.