Dihydroisocycloartomunin | 145643-97-6

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 黄酮类化合物
• 英文名称: Dihydroisocycloartomunin
• 英文别名: 3,8,10-trihydroxy-2-methoxy-11-(3-methylbut-2-enyl)-6-(2-methylprop-1-enyl)-6H-chromeno[4,3-b]chromen-7-one
• CAS: 145643-97-6
• 化学式: C₂₆H₂₆O₇
• 分子量: 450.5
• InChiKey: JFHXTPDDKBBGNW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.8
• 重原子数：
  33
• 可旋转键数：
  4
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.27
• 拓扑面积：
  105
• 氢给体数：
  3
• 氢受体数：
  7

文献信息

• Methods for producing agrimonia extracts with improved activity against hepatitis b virus and pharmaceutical and food compositions containing said extracts
  申请人：——

  公开号：US20040091555A1

  公开（公告）日：2004-05-13

  Disclosed are pharmaceutical and food compositions for preventing or treating hepatic disease, containing a pharmaceutically effective amount of an extract from a plant Agrimonia eupatoria L. Also, the present invention discloses a method of preparing a water-soluble extract from a plant of the genus Agrimonia, which which has improved efficacy in preventing or treating hepatic diseases, characterized by heating a mixture of a pulverized product of a plant of the genus Agrimonia and water at about 20° C. to 30° C. for about 7 days or more, and pharmaceutical and food compositions for preventing or treating a hepatic disease, containing a water-soluble extract prepared according to the method. Further, the present invention discloses a method of preparing an organic solvent-soluble extract from a plant of the genus Agrimonia, which has improved efficacy in preventing or treating hepatic diseases, comprising the steps of extracting a plant of the genus Agrimonia with an organic solvent, and removing an aqueous fraction and then obtaining an organic solvent-soluble fraction, and pharmaceutical and food compositions for preventing or treating hepatic disease, containing an extract prepared according to the method.

  公开了用于预防或治疗肝病的药物和食品组合物，其中含有药用有效量的植物提取物 Agrimonia eupatoria L.此外，本发明还公开了一种制备姬松茸属植物水溶性提取物的方法，该方法在预防或治疗肝病方面具有更好的疗效，其特征在于将姬松茸属植物的粉碎物和水的混合物在约20℃至30℃的温度下加热约7天或更长时间，以及用于预防或治疗肝病的药物和食品组合物，其中含有根据该方法制备的水溶性提取物。此外，本发明公开了一种从枸杞属植物中制备有机溶剂可溶性提取物的方法，该方法在预防或治疗肝病方面具有更好的疗效，包括以下步骤：用有机溶剂提取枸杞属植物，除去水溶液馏分，然后得到有机溶剂可溶性馏分；以及用于预防或治疗肝病的药物和食品组合物，其中含有根据该方法制备的提取物。
• US5981774A
  申请人：——

  公开号：US5981774A

  公开（公告）日：1999-11-09
• [EN] PYRANOFLAVONOID COMPOUNDS AND THEIR USE AS ESTROGEN RECEPTOR MODULATORS<br/>[FR] COMPOSES DE PYRANOFLAVONOIDE ET LEUR UTILISATION COMME MODULATEURS DE RECEPTEUR OESTROGENIQUE
  申请人：MERCK & CO INC

  公开号：WO2002058639A2

  公开（公告）日：2002-08-01

  The present invention relates to compounds derived from the plant Batocarpus costaricensis useful as estrogen receptor modulators. The compounds of the instant invention are ligands for estrogen receptors and as such may be useful for treatment or prevention of a variety of conditions related to estrogen functioning including: bone loss, bone fractures, osteoporosis, cartilage degeneration, endometriosis, uterine fibroid disease, hot flashes, increased levels of LDL cholesterol, cardiovascular disease, impairment of cognitive functioning, cerebral degenerative disorders, restinosis, gynacomastia, vascular smooth muscle cell proliferation, obesity, incontinence, and cancer, in particular of the breast, uterus and prostate.
• [EN] Methods for producing agrimonia extract with improved activity against hepatitis B virus and pharmaceutical and food compositions containing said extract<br/>[FR] METHODES DE PRODUCTION D'UN EXTRAIT D'AIGREMOINE AYANT UNE ACTIVITE AMELIOREE CONTRE LE VIRUS DE L'HEPATITE B, ET COMPOSITIONS PHARMACEUTIQUES OU ALIMENTAIRES CONTENANT CET EXTRAIT
  申请人：BIOKOREA CO LTD

  公开号：WO2003030921A1

  公开（公告）日：2003-04-17

  Disclosed are pharmaceutical and food compositions for preventing or treating hepatic disease, containing a pharmaceutically effective amount of an extract from a plant Agrimonia eupatoria L.. Also, the present invention discloses a method of preparing a water-soluble extract from a plant of the genus Agrimonia, which has improved efficacy in preventing or treating hepatic diseases, characterized by heating a mixture of a pulverized product of a plant of the genus Agrimonia and water at about 20°C to 30°C for about 7 days or more, and pharmaceutical and food compositions for preventing or treating a hepatic disease, containing a water-soluble extract prepared according to the method. Further, the present invention discloses a method of preparing an organic solvent-soluble extract from a plant of the genus Agrimonia, which has improved efficacy in preventing or treating hepatic diseases, comprising the steps of extracting a plant of the genus Agrimonia with an organic solvent, and removing an aqueous fraction and then obtaining an organic solvent-soluble fraction, and pharmaceutical and food compositions for preventing or treating hepatic disease, containing an extract prepared according to the method.