2-(3,4-dihydroxyphenyl)-8-[3,5,7-trihydroxy-2-(4-hydroxyphenyl)-3,4-dihydro-2H-chromen-4-yl]-3,4-dihydro-2H-chromene-3,5,7-triol

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 黄酮类化合物
• 英文名称: 2-(3,4-dihydroxyphenyl)-8-[3,5,7-trihydroxy-2-(4-hydroxyphenyl)-3,4-dihydro-2H-chromen-4-yl]-3,4-dihydro-2H-chromene-3,5,7-triol
• 化学式: C₃₀H₂₆O₁₁
• 分子量: 562.5
• InChiKey: KUODBSWFMJMVJV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.7
• 重原子数：
  41
• 可旋转键数：
  3
• 环数：
  6.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  201
• 氢给体数：
  9
• 氢受体数：
  11

文献信息

• PHENOLIC EXTRACTS OF ALMOND PEEL CONTAINING PROCYANIDINS, PROPELARGONIDINS AND PRODELPHINIDINS, AND METHOD FOR PREPARATION THEREOF
  申请人：Consejo Superior De Investigaciones Cientificas (60%)

  公开号：EP2165712A1

  公开（公告）日：2010-03-24

  This invention concerns phenolic extracts containing procyanidins, propelargonidins and prodelfinidins obtained from peel of the almond [Prunus dulcís (Mili.) D.A. Webb, Prunus amygdalus (L.) Batsch., Amygdalus dulcís (Mili.), Amygdalus communis (L.) or Prunus communis (L.)]. In particular, the objective is to obtain extracts rich in proanthocyanidins with type-A bonds. The preparation method for which protection is also claimed consists in: a) a maceration of plant material with organic solvents at 25-100 DEG C, b) purification by liquid-liquid extraction and/or adsorption or ion exchange chromatography, and c) optionally, a final drying. Also protected are the possible activities/properties of these extracts such as anti-oxidant activity and others, which determine the use thereof as a nutritional or health ingredient, and the use thereof in the cosmetic and pharmaceutical industry.

  本发明涉及从杏仁[Prunus dulcís (Mili.) D.A. Webb、Prunus amygdalus (L.) Batsch.、Amygdalus dulcís (Mili.)、Amygdalus communis (L.) 或 Prunus communis (L.)]果皮中提取的含有原花青素、丙炔基花青素和丙炔基花青素的酚类提取物。特别是，目的是获得富含带有 A 型键的原花青素的提取物。还要求保护的制备方法包括：a) 用有机溶剂在 25-100 摄氏度下浸泡植物材料；b) 用液-液萃取和/或吸附或离子交换色谱法提纯；c) 可选择最后干燥。这些萃取物可能具有的活性/特性，如抗氧化活性等也受到保护，这些活性/特性决定了萃取物可用作营养或保健成分，也可用于化妆品和医药行业。